Another amazing example of renomedullary interstitial cell tumor (medullary fibroma)- commonest kidney tumor of adults; bland spindle/stellate cells in myxoid stroma with stromal sclerosis #kidneymonth #KidneyCancerAwarenessMonth Michigan Pathology #gupath #pathology

Just as we have two eyes and two feet, duality is part of life ! Thoughts ? #tooclosetodiagnose #PathTwitter

Utility of UV Signature Mutations in the Diagnostic Assessment of Metastatic Head and Neck Carcinomas of Unknown Primary By K Colossi Furlan, D Saeed-Vafa, T M Mathew, et. al. rdcu.be/dLeIa #HeadNeckPathol #HNPJ #HeadandNeckPath #Pathology #ENTPath #PathologyTweet

paranasal sinus # invasive and angioinvasive fungal sinusitis.

Rete Testis • System transporting sperm🏊🏊🏊from which seminiferous tubules empty; then its delivers🏊to efferent ductules+epididymis where sperm🏊can mature • Female analogue: Rete ovarii • Pathology: Testicular tumors invading rete testis is still limited to testis (pT1)

Male patient in his 70s underwent radical orchidectomy for a slowly growing scrotal mass. Contributors: Laurence Galea, David Pan, Adam Scarlett GU Pathology Society (GUPS) Case of the Week: buff.ly/4dCrbdq Send your cases to buff.ly/4dEPAPD #GUpath #pathology

entpath # sinonasal papillomas # 1. oncocytic sinonasal papilloma vs 2. inverted sinonasal papilloma.

Urinary bladder - the prototypical scenario of carcinoma in situ with "denuding" pattern. Transition from normal to CIS to denuded epithelium, with only a small area of recognizable CIS. Sometimes known as "denuding cystitis" or "clinging CIS".

#Adrenal consult case Michigan Pathology with primary hyperaldosteronism - Aldosterone producing nodule + multiple aldosterone-producing micronodules. CYP11B2 IHC essential and one of the best IHC assays. #GoBlue

at first👁️of this high-power🔬from #GUpath TURBT, you could be🤨if this is hyperplastic MM vs true MP invasion add'l #LPpath📸highlight what I sometimes call "chewed-up" pattern MP invasion (haphazard MP engulfment by tumor with tiny viable islands present, mimicking hyperpl MM)

Cribriform High grade PIN is eliminated from the WHO 2022 update and now if you see this type of histologic pattern we have to call it atypical intraductal proliferation (AIP) -see red star Dr. Downes #USCAP2024 #gupath #pathology #pathologist #NIPPathX #pathresidents

#GUpath prostate bx shown to me as curbside consult from colleague what would you favor? 📸here with poll to follow⏬

Other SOX10+ non melanoma cells in sentinel lymph node: salivary gland tissue inclusion. Although common in paraparotid lymph nodes, they have also been described in unusual sites such as the pulmonary hilum (PMID: 21087984) #pathology #dermpath #dermatology #PathX #MedX

I usually never post anything outside of #pathology #healthcare But today is #Rakhi The day we tie the thread of protection on our brothers and sisters. In light of the horrific events surrounding the young doctor murdered in #Kolkata let’s unite for justice #JusticeForRGKar

1. Mucoepidermoid carcinoma, low grade, Warthin tumor-like variant (scanned). Predominantly cystic parotid gland neoplasm with a dense lymphoplasmacytic tumor associated lymphoid proliferation (TALP). A MAML2 gene rearrangement is present, confirming the diagnosis. #PathTwitter

📖 NUT Carcinoma 🔬Poorly differentiated epithelioid cancer requiring confirmation of NUTM1 rearrangement 😨Aggressive; 6.5 mo median survival 🗺️Thoracic/Mediastinal(51%); Head&Neck(40%) 🎨 NUT, p63 + Ki-67⬆️ ❗️Must have as Ddx for any poorly differentiated carcinoma+lymphoma

#GUpath nephrectomy: seemingly clear cell papillary renal cell tumor (CCPT) at high power mag, right? lower power👉🏽transitions away into traditional clear cell RCC (this tumor was VHL+ by NGS) ⏬

# entpath # Rushton bodies #Odontogenic keratocyst

#gupath #testis #mixed germ cell tumor # choriocarcinoma and teratoma.