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Not every study needs to have a power analysis, but every study needs a sample size justification. I discuss 6 approaches, and 6 ways to think about which effect sizes are of interest in the study you are planning. online.ucpress.edu/collabra/artic…

Predatory Journals jamanetwork.com/journals/jama/…

Gender and geographical bias in the editorial decision-making process of biomedical journals: a case-control study #OriginalResearch by Gayet-Ageron et al. #OpenAccess Link: bit.ly/41Z9sdQ

Great news! community.cochrane.org/news/embracing…

Death by p‑value: 5 critical care interventions which demonstrated meaningful treatment effects, high posterior probabilities of real benefit, yet missed conventional statistical significance: 💉 etomidate vs ketamine for RSI 🧫 beta-blockade in septic shock ⏱️ early vs late

"Data show that black doctors are more than twice as likely to be referred by their employers compared with their white colleagues, with those trained overseas at even greater risk." Work must continue to improve things, Abi Rimmer hears bmj.com/content/388/bm…

A panel of international experts give a strong recommendation that spine injections should not be given to adults with chronic back pain because they provide little or no pain relief compared with sham injections bmj.com/content/388/bm… Includes a #BMJInfographic

Just published #BMJ paper: strong against all interventional procedures for spine pain (joint radio frequency ablation; epidural injections; intramuscular injections, etc.) useless & harmful but lucrative. How to stop clear: stop paying. But can it happen? bmj.com/content/388/bm…

Our trial shows an e-learning program can improve physios’ beliefs about low back pain! - summary: australian.physio/inmotion/back-… - full paper: sciencedirect.com/science/articl…

Not sure who's still here, but anyway! We collected all the placebo controlled trials for non-surgical Rx on back pain together in a systematic review. It was pretty epic, and pretty sobering results-wise. Hope you like it. ebm.bmj.com/content/early/…

Do clinical practice guidelines for low back pain include predatory journal or retracted publications? A meta-resea… pubmed.ncbi.nlm.nih.gov/40156953/

It's been a while but another Evidence in Practice article is out: an explainer on odds and risk, which are used to measure dichotomous outcomes (recovered/unrecovered, injured/not injured etc) Direct message or email if you can't access and want a pdf jospt.org/doi/10.2519/jo…

Big news for #EBM! Just out in #BMJ, ROBUST-RCT, pristinely developed, innovative, simple, user-friendly instrument for risk of bias assessment in #RCTs far superior to anything before, will become standard outside of Cochrane and in #Cochrane if they let folks use it.

A major update to the CONSORT reporting guidance for clinical trials was published last week. 📌 CONSORT 2025 replaces all previous versions and should be used from now on. So what’s new and what’s different? 1/7 #MethodologyMonday #116 (COI - I am a co-author)

NEW PAPER: Updated SPIRIT-2025 for reporting protocols of randomised trials is now available in the The BMJ JAMA The Lancet Nature Medicine PLOS Medicine —> bmj.com/content/389/bm… #openscience #transparency #medX #statsX #epiX

As previous post, a 2 minute video in which I describe the second of 7 Core GRADE articles appearing in the BMJ. This one, published today, shows to choose the target of the certainty rating and address imprecision in systematic reviews and guidelines. linkedin.com/posts/guyattgh…

Our new paper is published 💥 The primary argument is that surgery is not, and cannot be, a "true" placebo in the classical sense. This argument leads to the hypothesis that the improvement in pain observed after sham surgeries is mediated by the potent general and local

Do you know your Odds Ratio from your Risk Ratio 🤔 If not, don't fear, Dr Kamper is back with the popular #EvidenceInPractice series to explain all ... Read more ➡️ ow.ly/ZcwV50Vx61u #yourJOSPT

Just published #JAMA Intern Med demonstrating that many #SystematicReviews of #RCTs include retracted studies and their inclusion can substantially influence results. Search for #retractions should now be standard in systematic reviews. #EBM #Medicine pubmed.ncbi.nlm.nih.gov/40163084/

Ground-breaking, still highly relevant paper established that specific health status measurement #instruments are better at detecting treatment effects – that is, more responsive – than are generic instruments. pubmed.ncbi.nlm.nih.gov/12589870/