PCF Science (@pcf_science) 's Twitter Profile
PCF Science

@pcf_science

The official Twitter account for scientific news from the Prostate Cancer Foundation. Follow us at @PCFNews @ PCF-science.bsky.social

ID: 783751524308484096

linkhttp://pcf.org calendar_today05-10-2016 19:31:39

10,10K Tweet

5,5K Takipçi

650 Takip Edilen

Adam B. Weiner, MD (@adam_weiner535) 's Twitter Profile Photo

🚨Polygenenic Risk Score for #prostatecancer Screening🚨 📰NEJM 🔑Of patients w/ a PRS>90th %-tile 1⃣ 43% of those w/ PSA<3 had csPCa (≥GG2) 2⃣ 15% of those w/ a negative MRI had csPCa 🔗shorturl.at/iDhOP UroToday.com Renal & Urology News Urology Times GU Cast | Urology podcast! Prostate Cancer Foundation

🚨Polygenenic Risk Score for #prostatecancer Screening🚨

📰<a href="/NEJM/">NEJM</a> 

🔑Of patients w/ a PRS&gt;90th %-tile
1⃣ 43% of those w/ PSA&lt;3 had csPCa (≥GG2)
2⃣ 15% of those w/ a negative MRI had csPCa 

🔗shorturl.at/iDhOP

<a href="/urotoday/">UroToday.com</a> <a href="/renalandurology/">Renal & Urology News</a> <a href="/UrologyTimes/">Urology Times</a> <a href="/gu_onc/">GU Cast | Urology podcast!</a> <a href="/PCFnews/">Prostate Cancer Foundation</a>
Adam B. Weiner, MD (@adam_weiner535) 's Twitter Profile Photo

🚨AR signaling and lncRNA🚨 📰Just published in Science Advances 👉Qi Cao's lab NM Urology show lncRNA PRCAT71 plays a role in stabilizing AR mRNA in #prostatecancer progression 🙏Thankful to be able to play a small role in this remarkable work 🔗shorturl.at/6tg3z

🚨AR signaling and lncRNA🚨

📰Just published in <a href="/ScienceAdvances/">Science Advances</a> 

👉Qi Cao's lab <a href="/NM_Urology/">NM Urology</a> show lncRNA PRCAT71 plays a role in stabilizing AR mRNA in #prostatecancer progression 

🙏Thankful to be able to play a small role in this remarkable work

🔗shorturl.at/6tg3z
Tyler Seibert MD PhD (@tylersbrt) 's Twitter Profile Photo

THIS 👇🏼 is what we do it all for!! Cancer research and oncology. It’s all so people like Tony can spend beautiful days with loved ones and loved ones can enjoy the company of people like Tony. 👏🏻👏🏻❤️ PCF Science ASCO ASTRO ESMO - Eur. Oncology ESTRO European Association of Urology (EAU) Amer. Urol. Assn.

Adam B. Weiner, MD (@adam_weiner535) 's Twitter Profile Photo

🚨Can the transcriptome reveal therapeutic vulnerabilities in localized #prostatecancer?🚨 👉Check out our analysis of >140k tumor samples in European Urology Oncology 🔗shorturl.at/k0J3H

🚨Can the transcriptome reveal therapeutic vulnerabilities in localized #prostatecancer?🚨

👉Check out our analysis of &gt;140k tumor samples in <a href="/EurUrolOncol/">European Urology Oncology</a> 

🔗shorturl.at/k0J3H
Stacy Loeb, MD (@loebstacy) 's Twitter Profile Photo

🚨Recruiting U.S. clinicians who manage patients w/ advanced #prostatecancer (e.g., med onc, rad onc, urology, APPs, RD's) for a 1h anonymous virtual interview about nutrition & lifestyle counseling ($40 gift card) -see flyer for more details & contact info. Please help share!

🚨Recruiting U.S. clinicians who manage patients w/ advanced #prostatecancer (e.g., med onc, rad onc, urology, APPs, RD's) for a 1h anonymous virtual interview about nutrition &amp; lifestyle counseling ($40 gift card) -see flyer for more details &amp; contact info. Please help share!
Prostate Cancer Foundation (@pcfnews) 's Twitter Profile Photo

At PCF, we advocate for early and regular prostate cancer screenings. In the wake of former President Biden’s diagnosis, Phillip Koo, MD spoke with the The Washington Post about this philosophy and why we believe that early screening and detection is critical. bit.ly/3H1RoqZ

Tyler Seibert MD PhD (@tylersbrt) 's Twitter Profile Photo

Very high inter-reader variability is the achilles heel of #prostateMRI What if #prostateMRI could be like a lab test that gives a quantitative value indicating risk of #ProstateCancer? New 📜 Journal of Urology 🧵1/x Amer. Urol. Assn. European Association of Urology (EAU) UroToday.com PCF Science

Very high inter-reader variability is the achilles heel of #prostateMRI

What if #prostateMRI could be like a lab test that gives a quantitative value indicating risk of #ProstateCancer?

New 📜 <a href="/JUrology/">Journal of Urology</a> 

🧵1/x
<a href="/AmerUrological/">Amer. Urol. Assn.</a> <a href="/Uroweb/">European Association of Urology (EAU)</a> <a href="/urotoday/">UroToday.com</a> <a href="/PCF_Science/">PCF Science</a>
Michael Hofman (@drmhofman) 's Twitter Profile Photo

Stunning research from Edmond Kwan on ctDNA in theranostics: 🧬Low ctDNA predicts better response with ¹⁷⁷Lu-PSMA-617 vs. cabazitaxel chemotherapy ⚠️PTEN alterations linked to worse outcomes on cabazitaxel 🧪ATM defects tied to favorable PSMA-617 results 🩻PET quantitative

Stunning research from <a href="/EdmondMKwan/">Edmond Kwan</a> on ctDNA in theranostics:
🧬Low ctDNA predicts better response with ¹⁷⁷Lu-PSMA-617 vs. cabazitaxel chemotherapy
⚠️PTEN alterations linked to worse outcomes on cabazitaxel
🧪ATM defects tied to favorable PSMA-617 results
🩻PET quantitative
Edmond Kwan (@edmondmkwan) 's Twitter Profile Photo

On the eve of #ASCO25, I am delighted to share results from the correlative analyses of the ANZUP phase II TheraP study, now published in Nature Medicine. Massive effort supported by dedicated co-investigators, coordinators, patients & families from 11 study sites across

On the eve of #ASCO25, I am delighted to share results from the correlative analyses of the <a href="/ANZUPtrials/">ANZUP</a> phase II TheraP study, now published in <a href="/NatureMedicine/">Nature Medicine</a>. Massive effort supported by dedicated co-investigators, coordinators, patients &amp; families from 11 study sites across
Neeraj Agarwal, MD, FASCO (@neerajaiims) 's Twitter Profile Photo

Congrats #MichaelOng SOUMYAJIT ROY for oral Ab#5002 ASCO #ASCO25👉bit.ly/43NyyfY👉Real-world IRONMAN registry of mHSPC #prostatecancer (n=1288 pts)👉PSA<0.02 after 6-12 mo of Rx had best prognosis (3-yr OS 92.7%)👇Dan George OncoAlert UroToday.com PCF Science

Congrats #MichaelOng <a href="/Soum_Roy_RadOnc/">SOUMYAJIT ROY</a> for oral Ab#5002 <a href="/ASCO/">ASCO</a> #ASCO25👉bit.ly/43NyyfY👉Real-world IRONMAN registry of mHSPC #prostatecancer (n=1288 pts)👉PSA&lt;0.02 after 6-12 mo of Rx had best prognosis (3-yr OS 92.7%)👇<a href="/Daniel_J_George/">Dan George</a> <a href="/OncoAlert/">OncoAlert</a> <a href="/urotoday/">UroToday.com</a> <a href="/PCF_Science/">PCF Science</a>
Ravi A Madan M.D. (@dr_ravimadan) 's Twitter Profile Photo

Updated data from #PSMA monitoring study in #BCR #ProstateCancer ASCO #ASCO25 Stop by & see our poster on Monday morning You can see what happens to this pt at 6 months 10+ LNs How would you have managed this case? Trial continues to accrue National Cancer Institute clinicaltrials.gov/study/NCT05588…

Updated data from #PSMA monitoring study in #BCR #ProstateCancer <a href="/ASCO/">ASCO</a> #ASCO25 

Stop by &amp; see our poster on Monday morning

You can see what happens to this pt at 6 months 10+ LNs

How would you have managed this case?

Trial continues to accrue <a href="/theNCI/">National Cancer Institute</a>

clinicaltrials.gov/study/NCT05588…
Neeraj Agarwal, MD, FASCO (@neerajaiims) 's Twitter Profile Photo

Just in from ASCO #ASCO25 👉📢 Finally a T-cell engager in #prostatecancer mCRPC with minimal CRS syndrome (only grade 1, all outpatient dosing) and promising efficacy👇 Congrats #drbaldini Mark Stein and team Journal of Clinical Oncology OncoAlert UroToday.com PCF Science

Just in from <a href="/ASCO/">ASCO</a> #ASCO25 👉📢 Finally a T-cell engager in #prostatecancer mCRPC with minimal CRS syndrome (only grade 1, all outpatient dosing) and promising efficacy👇 Congrats #drbaldini <a href="/drmnstein/">Mark Stein</a> and team <a href="/JCO_ASCO/">Journal of Clinical Oncology</a> <a href="/OncoAlert/">OncoAlert</a> <a href="/urotoday/">UroToday.com</a> <a href="/PCF_Science/">PCF Science</a>
Michael Hofman (@drmhofman) 's Twitter Profile Photo

#VIOLET Study of Terbium-161 (Tb-161) Beta/Auger therapy ASCO #ASCO25 First prospective trial of Terbium-161 in any tumour type 🟣 30 patient trial in prostate cancer. No dose limiting toxicities at highest level of radioactivity (7.4 GBq) 🟣 Very few side effects: 1 grade 3

#VIOLET Study of Terbium-161 (Tb-161) Beta/Auger therapy <a href="/ASCO/">ASCO</a> #ASCO25

First prospective trial of Terbium-161 in any tumour type
🟣 30 patient trial in prostate cancer. No dose limiting toxicities at highest level of radioactivity (7.4 GBq)
🟣 Very few side effects: 1 grade 3
Ravi A Madan M.D. (@dr_ravimadan) 's Twitter Profile Photo

Great discussions @asco #ProstateCancer posters #ASCO25 #PSMA+ #BCR is an indolent process & pts do NOT require urgent therapy in most cases We should be ⚠️ cautious about over-treatment 🔗shorturl.at/NtxdF Trial continues to accrue National Cancer Institute clinicaltrials.gov/study/NCT05588…

Great discussions @asco #ProstateCancer posters #ASCO25

#PSMA+ #BCR is an indolent process &amp; pts do NOT require urgent therapy in most cases

We should be ⚠️ cautious about over-treatment 

🔗shorturl.at/NtxdF

Trial continues to accrue <a href="/theNCI/">National Cancer Institute</a>

clinicaltrials.gov/study/NCT05588…
Prostate Cancer Foundation (@pcfnews) 's Twitter Profile Photo

Breaking News: Darolutamide is now FDA-approved for mHSPC. It’s used with standard hormone therapy as part of combination treatment—the gold standard for mHSPC. Learn why this matters: pcf.org/the-new-standa…

Breaking News: Darolutamide is now FDA-approved for mHSPC.

It’s used with standard hormone therapy as part of combination treatment—the gold standard for mHSPC.

Learn why this matters: pcf.org/the-new-standa…
Joaquin Mateo (@quimmateo) 's Twitter Profile Photo

Prof. Mary-Claire King has been named the 2025 Princess of Asturias Award laureate for science — amazing recognition. Her work on the BRCA1/2 genes led to transforming cancer care, including for men with #ProstateCancer fpa.es/en/princess-of… PCF Science CRIS contra el cáncer

David P. Labbé, PhD (@davidp_labbe) 's Twitter Profile Photo

We are hiring a 👩‍🔬 Research Assistant 👨‍🔬 to work on cutting-edge dietary interventions to potentiate DNA damaging therapies in prostate cancer. Come working with us at the @CUSM_MUHC McGill Dept of Surg McGill University! Please share: bit.ly/43V72fs Society for Basic Urologic Research | SBUR PCF Science

Tyler Seibert MD PhD (@tylersbrt) 's Twitter Profile Photo

Michael Jung kicking off the PCF Science Coffey-Holden #ProstateCancer Academy discussing drug discovery His work to make enzalutamide has certainly made an impact!! 👏🏻👏🏻

Michael Jung kicking off the <a href="/PCF_Science/">PCF Science</a> Coffey-Holden #ProstateCancer Academy discussing drug discovery

His work to make enzalutamide has certainly made an impact!! 👏🏻👏🏻
Salma Kaochar (@kaochar2) 's Twitter Profile Photo

#PCFAcademy PCF Science Day 2 session on Cell Death… uff.. each layer of understanding peels back to reveal deeper complexities.. the more I learn, I realize how little I really know 🫣