We're not going to '3rd dose' our way out of the pandemic just like we were never going to mask our way out. Vaccines (especially 1st & 2nd but also 3rd), masks, rapid tests, ventilation, sound policy, etc... ...each is a helpful tool providing additional/incremental benefit.

How to reduce your chance of dying from Covid by 99%? Get vaccinated and a booster. One of the most impressive graphs I've seen for the impact of vaccination in the US pandemic (thanks Edouard Mathieu @OurWorldinData for re-plotting my makeshift graph from earlier today)

This filtered @Nextstrain build gives a nice visual display of how distant the Omicron family is from everything else, & how different BA.1 (21K) & BA.2 (21L) are from each other. Distance is in mutations. nextstrain.org/ncov/gisaid/gl…

Just published @nature The impact of #Covid on the brain: the 1st longitudinal imaging study before and after infection, with controls nature.com/articles/s4158… Reduction of grey matter, brain size, cognitive decline

We've been learning a lot about how Omicron BA.1 and BA.2 compare in recent weeks. Here's a summary table that I compiled and will update when more data become available

Covid shouldn't even be in the top 10 causes of death in the US if we consistently used all the tools available. Yet we're still now losing the lives of 500 Americans each day.

Good graphic for how Omicron (and its various BA. family lineages) gets into cells, which differs from prior variants. A nice explainer for its hyper-contagiousness scientificamerican.com/article/omicro… Scientific American by Megan Scudellari and @FalconieriV

"These findings suggest an unexpected alternative mechanism for #LongCovid. Rather than persistent immune activation, we observed abnormal immune downmodulation, which is normalized by leronlimab [a CCR5 antibody]" academic.oup.com/cid/advance-ar…

🆕 The Lancet Respiratory Medicine Protection vs Omicron hospitalization via Pfizer mRNA vaccination falls off 3 months after the booster/3rd shot thelancet.com/journals/lanre… Kaiser Permanente Southern California

Today health authorities in #DRC declared an outbreak of #Ebola after a case was confirmed in Mbandaka. This is the 3rd outbreak in the province since 2018. So far, just one case has been confirmed. ➡️ ow.ly/qIPt50IQx1r

Uganda confirms an outbreak of Ebola Virus Disease (EVD) in Mubende District, Uganda.   The confirmed case is a 24 year old male a resident Ngabano village of Madudu Sub County in Mubende District presented with EVD symptoms and later succumbed.

Our comprehensive review of #LongCovid has just been published nature.com/articles/s4157… Phenomenal work by Hannah Davis Lisa McCorkell julia Nature Reviews Microbiology

Important new report on #LongCovid and the brain demonstrating persistence of the virus spike protein, throughout the body and particularly the skull-meninges axis, both in humans and the mouse model biorxiv.org/cgi/content/sh… by Ali Max Erturk Zhouyi Rong HongchengMAI Saketh Kapoor, PhD

The end of the #COVID19 global health emergency is a moment for reflection. The painful lessons we have learned, the investments we have made, and the capacity we have built must be transformed into meaningful and lasting change.

New The Lancet Respiratory Medicine A pathophysiological model of #LongCovid based on persistence of the #SARSCoV2 virus, and review of all the supportive evidence thelancet.com/journals/lanre…

Yesterday, the emergency committee for #mpox met and recommended to me that the outbreak no longer represents a public health emergency of international concern. I have accepted that advice, and am pleased to declare that mpox is no longer a global health emergency.

Persistence of #SARSCoV2 virus, or parts of it, in 11 studies of children for weeks to months after acute infection, independent of severity thelancet.com/journals/lanmi… The Lancet Microbe #LongCovid

A third of people are Blood Group A. #SARSCoV2 preferentially infects these cells "providing a direct link between ABO blood group expression and [Covid] infection" ashpublications.org/blood/article/… ASH

18 years ago today, 11 SEALs & 8 Army Night Stalkers made the ultimate sacrifice, as they were killed in action behind enemy lines. I am so grateful my brother, Marcus, made it home from Operation Red Wings. We'll never forget the brave warriors who gave it all for our country.

The emergence of a new clade of #mpox, its rapid spread in eastern #DRC, and the reporting of cases in several neighbouring countries are very worrying. On top of outbreaks of other mpox clades in DRC and other countries in Africa, it’s clear that a coordinated international