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Wow! Practice changing EARLY TAVR RCT. For a long time, we waited for aortic stenosis patients to become symptomatic before considering therapy, based on old data (risk of surgery vs watchful waiting). ASYMPTOMATIC patients with severe AS, TAVR leads to a major reduction in MACE

EARLY TAVR my view… Imagine this scenario: you are a pt with asymptomatic aortic stenosis and are offered to participate in a trial in which you may receive TAVR or conservative treatment…until you develop symptoms and then you can get a TAVR (probably free) TCTMD Mamas A. Mamas

Now lets see what was that number in EARLY TAVR 👇3x as high as natural history studies !!! That is the power of randomization !!!

PEERLESS- Inari large bore thrombectomy vs catheter directed thrombolysis in intermediate risk PE ☝🏾First RCT in PE for MT vs CDT 🔑KEYS Very low mortality and bleeding in both groups Heterogeneity with CDT group No anticoagulation group Results: MT met primary endpoint

EARLY-TAVR Looks like primary composite driven by conversion to early TAVR... not sure this answers the question, other than telling us AS progresses? Why would more CVA occur in surveillance group? John Mandrola, MD NEJM nejm.org/doi/full/10.10…

The trial that I’m most excited about to come out of #TCT2024. Exciting news for intermediate risk PE’s!

At Emory, always pushing the boundaries of innovation! TCT2024 live case. First-in-man electrosurgical mitral commissurotomy (CLEFT). Novel approach for mitral stenosis with high Wilkins score and prohibitive surgical risk #TCT2024 Adam Greenbaum Vasilis Babaliaros Anton Camaj, MD, MS

When I was a third year medical student on a cardiology rotation, we had a quiet afternoon and I was chatting with one of the attendings. He told me that he had replaced another cardiology attending who had recently passed away. The new attending was terrified in taking up some

Watching Gen Z men veer right hits different for Millennials. We lived through Columbine, 9/11, the Iraq War, 2008 crash, 2016 election, covid, abortion bans, & now this. We watched institutions repeatedly fail us while older generations selfishly protected the status quo. 🧵1/

3 years ago my good friend Jonathan D. Moreno approached me about this crazy idea to fill a much needed gap in heart failure education (1/3).

All star clinical pearls for #echofirst in HCM, MR, and LVOT obstruction 🌟

Happy to share that I’ll be presenting abstracts at #ACC2025 and #ISHLT 2025! Can’t wait to see everyone there, network, and talk HF and Cardiogenic Shock 😁 BSW Heart Hospital Plano Cardiology Fellowship

"Does lowering LDL-C to very low levels result in long-term cognitive impairment?" 🧠🫀 I've heard this question many times. Now we have long-term data. A 🧵 on our new NEJM Evidence paper: evidence.nejm.org/doi/full/10.10… TIMI Study Group Robert Giugliano Michelle O'Donoghue

WEDGE-HCM #Editorial: Exercise improves cardiac hemodynamics in non-obstructive HCM, suggesting benefits like better LV compliance. A step forward for exercise as therapy @mpayers_md ahajournals.org/doi/full/10.11…

Curious about the impact of "door-to-RV unload time" in PE treated w/ percutaneous interventions? Dive into our latest article in CircInterventions to find out👇 🔗ahajournals.org/doi/10.1161/CI… & don't miss the insightful editorial by Sanjum S. Sethi MD, MPH ⤵️ 🔗ahajournals.org/doi/10.1161/CI… Sripal Bangalore

Is 70 the age that we should be using for a cutoff of #HeartTransplantation? These results show excellent survival outcomes from the SRTR registry in our oldest recipients in the U.S. Erik Henricksen 🔗: jhltonline.org/article/S1053-…

The MAPLE-HCM study evaluates #aficamten vs #metoprolol to potentially redefine first-line therapy standards in hypertrophic obstructive cardiomyopathy. Details of the study design here: jacc.org/doi/10.1016/j.… #JACCHF #oHCM #HCMAwarenessDay Pablo Garcia-Pavia Neal Lakdawala

Great to catch-up with friends and mentors at #ISHLT2025. Aasim Afzal MD FHFSA Parag Kale Antoinette Birs, MD Serafim Perdikis Marika Harada, MD Michael Vu, DO. BSW Heart Hospital Plano Cardiology Fellowship UC San Diego Cardiology Fellows The ISHLT Women in Heart Transplantation and MCS Women As One