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New! Online now: Emerging debates and resolutions in brown adipose tissue research dlvr.it/TGdgZX

New article by Pedro Latorre Muro published in Nature Cell Biology Molecular mechanisms of ER stress-inducible chaperones mediating outer mitochondrial membrane TOM70 insertion protective against diet-induced obesity and diabetes rdcu.be/d5ptF

Cell-death induced immune response and coagulopathy promote cachexia in Drosophila. Ankita Singh, Yanhui Hu, Raphael Fragoso Lopes, Liz Lane, Hilina Woldemichael, Charles Xu, Namrata D. Udeshi, Steven A. Carr, Norbert Perrimon doi: doi.org/10.1101/2025.0…

Is this why all you fasting guys are bald? cell.com/cell/abstract/…

The Journal of Lipid Research is excited to present 'Recent Advances in Lipid Research', a collection of research articles exploring cutting-edge topics in lipid science, including lipoprotein biology, fatty acids, and spatial lipidomics. Read more 👉 spkl.io/6011fgouR

Excited to share our new work Science Advances in collaboration with the Labesse lab. We report the high-resolution Cryo-EM structure of human NADK, revealing a tetrameric organization with distinct structural and functional features. science.org/doi/10.1126/sc…

Rhodoquinone carries electrons in the mammalian electron transport chain: Cell cell.com/cell/fulltext/…

Wow very big news for biomedical research

Happy to share the final version of this work where we incorporated isotope labeled CO2 data into mass spec-based flux analysis framework to build a whole-body flux model of energy metabolism. Full article access here: authors.elsevier.com/a/1keM55WXUlaX… Bo Yuan, Ph.D.

Ergothioneine is an atypical amino acid to which many health benefits in humans have been ascribed. Here we determine the direct protein target of ergo binding and how it functions in mitochondria and exercise. authors.elsevier.com/c/1kdIa5WXUlaX…

New! Online now: Leptin enhances the intracellular thyroid hormone activation in skeletal muscle to boost energy balance dlvr.it/TJ6dzg

Thank you! This is an incredible honor. I would like to thank my mentors, colleagues, and all the fellows who have worked with me over the years - Please come join us at ADA in Chicago!

“Shunt-ing” down obesity with novel endogenous metabolites dlvr.it/TJTTtH

From “preprint” to “in press”! Congrats Martín Valdearcos Dr. Rachel Lippert and the rest of our outstanding team. Diabetes Center at UCSF UC San Francisco #microglia #hypothalamus Microglia mediate the early-life programming of adult glucose control: Cell Reports cell.com/cell-reports/f…

The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research | Nature Metabolism ⁦Nature Metabolism⁩ Great collaboration led by ⁦Satchin Panda⁩ and team! nature.com/articles/s4225…

Excited to share ‘Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins’, by phenomenal superstar postdoc Aakriti Jain Aakriti Jain and amazing collaborators Rushika M. Perera, Guido Bommer, Charly Craik and James Olzmann: science.org/doi/10.1126/sc…

GLP-1 agonists have transformed life for many people with type 2 diabetes and obesity. The 2025 Breakthrough Prize honors Daniel Drucker, Joel Habener, Jens Juul Holst, Lotte Bjerre Knudsen and Svetlana Mojsov for seminal contributions to GLP-1's discovery, characterization and

Adipose tissue generates heat even in the absence of UCP1. How does it work? Our new work identifies a molecular “resistor” of Ca2+ cycling that makes heat and controls energy metabolism through a UCP1-independent mechanism. sciencedirect.com/science/articl…

New! Online now: Identification of a molecular resistor that controls UCP1-independent Ca2+ cycling thermogenesis in adipose tissue dlvr.it/TK5v2N

Thrilled to share our new Nature Cell Biology paper, led by our amazing student Dohun Kim: Mitochondrial NADPH powers mitochondrial fatty acid synthesis to sustain lipoylation, mitochondrial translation, and oxidative metabolism. rdcu.be/eiyH7