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We are thrilled to present a new #enzyme to the world, the first shown to break the man-made carbon-silicon bonds in #siloxanes, which are persistent in the environment. caltech.edu/about/news/tea…

Congrats to team!

🩺Penn Medicine spotlight: today we recognize Dr. Nduka Amankulor, a renowned brain surgeon and Director of the Penn Medicine Brain Tumor Center. Nearly 3 years ago, Dr. Amankulor performed a complex glioblastoma operation to remove a malignant brain tumor in Georgina Weber.

There's never been a disease-modifying drug for Parkinson's disease to slow its progression. Now there may be two emerging. —GLP-1 nejm.org/doi/abs/10.105… NEJM —anti-synuclein antibody nature.com/articles/s4159… NATURE.med

(1/n) excited to share that our study on how condensate-promoting ENL mutations drive tumorigenesis is out at Cancer Discovery! aacrjournals.org/cancerdiscover…

GBM cell states are fluid, but manipulable

We are thrilled to announce the recipients of the 2025 Epigenetics Institute At-Large Pilot Grants! We look forward to seeing the progress of these projects in the next year! Yanxiang Deng Liling Wan Eric Joyce Richard Phillips Kahlilia Morris-Blanco

Truly visionary work. May end up being the most impactful technologies over the next few decades in biomedical science. Congrats to Dr Baker, Demis Hassabis and Dr Jumper!!!

Thrilled to be a named an National Cancer Institute #CancerMoonshotScholar. All thanks to the team, mentors #FrancesJensen and our precious patients as we work toward better treatments for glioma University of Pennsylvania Neurology Penn Medicine - Abramson Cancer Center Penn Epigenetics

Award-winning work by Yusha Sun Song and Ming Labs at #SNO2024

Thanksgiving lunch! Grateful for this team 🙏🏽🦃

It seems easy to make fun of basic science – for example why would you want to study bacterial immune systems? But then you would have to admit that that’s exactly what led to the discovery of using CRISPR as an insanely good technology for genome engineering.

Congrats Christina Jackson, MD

In the future soon, we will be able to communicate with many intelligent animal species - can't wait to better understand what my dog🐶is saying! Congrats to the DolphinGemma team building on our Gemma models - the most powerful single GPU/TPU open source models out there!

Congrats to newly minted Dr Dejauwne Young Albert Einstein College of Medicine - Official MD PhD candidate and future neurosurgeon scientist, on his thesis defence. Hugely impressed by your intellect and tenacity. Coming to a lucky neurosurgery residency soon, no doubt! Nduka Amankulor, MD BrainRepairLab (Dr. Isaac Chen Lab) @bryandchoi

Beautiful work, congrats Ophir Shalem GB

A new study in Nature challenges long-standing views on how Group 3/4 #medulloblastomas develop. Study group led by Prof. S. Pfister argue that large-scale chromosomal alterations, not oncogene mutations, are the earliest events in tumor initiation. 🧵🧵🧵 1/n

Amazing

New paper alert! In collaboration with the Adrian Bracken and Brien labs in Molecular Cell we identify a specific PRC1 complex which is hijacked in #DMG to drive the malignant state. Lays the framework for a new therapeutic strategy! University of Pennsylvania Neurology Penn Epigenetics Penn Medicine - Abramson Cancer Center

New in Nature Medicine, our researchers have found that a dual-target CAR T-cell therapy approach shows promise for slowing tumor growth in glioblastoma. Stephen Bagley DrORourke Penn Medicine - Abramson Cancer Center Penn Medicine ➡️ spr.ly/6011NCoGT