🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

🚨Reminder: Abstracts are OPEN for the best conference of the year! Submit your abstract for the premier physician-scientist meeting with APSA, AAP, & ASCI! Network, find mentors, attend sessions, & more. 📍Submit here: jointmeeting.org

Discover a new genetic link to retinal detachment! 🧬👀 We'll be ASHG poster 5105 to discuss VSX2 variants, associated with a 6-fold increased risk of dominant retinal detachment using the UKB Stop by from 2:30pm-4:30pm today! BCM Department of Molecular and Human Genetics Ryan Dhindsa #ASHG2024

Are you at ABRCMS in Pittsburgh this week? Stop by and see the BCM GSBS at booths 1524 and 1526. We’ve got a variety of programs available for wherever you are in your scientific journey. Come say hi and learn more!

🧑‍⚕️ Interested in an MD/DO-PhD? Check our updated Application Guide for essential tips! 📚✨ Full guide: tinyurl.com/APSAApplicantG… #MDPhD #DODualDegree #FuturePhysicianScientists #MedSchoolApps #PhysicianScientist #APSA

In collaboration with Reuben Saunders, Jonathan Weissman's Lab, and Xiaowei Zhuang, we are very excited to release Perturb-Multi: a platform for pooled multimodal genetic screens in intact mammalian tissue. Check it out! biorxiv.org/content/10.110…

Our wonderful collaborators on the Perturb-Multi work (biorxiv.org/content/10.110…) are now here and on the other app, at ZhuangLab

One of the biggest mysteries in Alzheimer's disease that is yet to be solved is the pathogenic mechanism of ApoE4 variant (and the protective mechanism of ApoE2). A new study reports that LDL receptor binding affinity in brain cells linearly increase from E2 to E3 to E4 and so

Awesome White Elephant/Holiday Party yesterday with BCM MD/PhD Program ! It’s always such a great time getting together and celebrating!

Thank you for the support! We will have information tailored for MD/PhD students and undergraduates. Travel awards are available for students outside the Houston metro area. Registration is free! physicianscientists.org/mpage/south-re… APSA BCM MD/PhD Program #doubledocs

Spliceopathies are a group of rare diseases caused by inborn errors in RNA splicing mechanisms. The causative mutations could be challenging to identify as they are often noncoding and sit within snRNA genes. Here the authors use a transcriptomics-first approach to screen

Fabulous energy here today as we host the south regional APSA conference. Kudos to the student organizers for a great turnout!

Thrilled the APSA South Regional Meeting was a success! 🎉 Huge thanks to attendees, organizers, BCM MD/PhD Program & Texas Children's hosting, and APSA for making it happen! Interested in hosting next year’s meeting? DM me—we’ve got resources to share! #APSA #PhysicianScientists

Check out our two new papers with new single-cell tech/methods/data! 1. Phospho-seq: Multi-modal profiling of intracellualar proteins nature.com/articles/s4146… 2. Systematic Perturb-seq of signaling regulators (2.6M cells, 6 cell lines, 1500 perturbations) nature.com/articles/s4155…

Long-range enhancer-controlled genes are hypersensitive to regulatory factor perturbations cell.com/cell-genomics/…

Amazing APSA South Regional Meeting this year! It was a treat talking to undergrads about the work we do BCM MD/PhD Program From the Labs at Baylor College of Medicine and providing mentorship/guidance on their next steps as future physician scientists. And huge shoutout to our amazing chair Daniel Brock!

News: NIH researchers develop eye drops that slow vision loss in animals nih.gov/news-events/ne…

🚀 Our perspective is out in nature! We present a roadmap for Multimodal Foundation Models (MFMs) — large AI models pretrained across multi-omics and multi-timepoint data — to serve as the computational backbone for building virtual cells. Read the full paper in Nature:

Today at the #JointMeeting2025, Svetlana Mojsov, 2024 #LaskerLaureate, gave an impressive overview of how her research on GLP-1 revolutionized the field of glucose metabolism. Her findings led to development of novel therapeutics for #diabetes and #obesity. APSA

Drop by poster B0008 today to learn about genetic risk factors for retinal detachment! We found that variants in VSX2 were associated with an increased risk of retinal detachment in the UK Biobank. Shout out to my PIs Ben Frankfort and Ryan Dhindsa! ARVO #visionscience

I used to spend months agonizing over my research direction. Now, I can find a compelling PhD topic in just one day. The secret? This guide: