GammaTile by GT Medical Technologies, Inc. has announced the enrollment of the first patient into the GESTALT (GammaTile Enhanced Stupp ALTernative Trial) of GammaTile Surgically Targeted Radiation Therapy (STaRT) for patients with newly diagnosed glioblastomas. Read more here: ow.ly/gLex50L72MQ

Researchers tested a subcutaneously implanted catheter-pump system capable of repeated, chronic CED of topotecan into the brain in five patients with recurrent glioblastoma. @columbianeuro Michael Argenziano Peter Canoll Matei Banu DOI:doi.org/10.1016/S1470-…

Just a snapshot of the funding opportunities you can find on our website. Find these, and more, here - cbtddc.org/funding-opport… Cancer Research Horizons Brain Research UK Anticancer Fund Pan Pantziarka UK Research and Innovation National Institute for Health and Care Research Biotechnology and Biological Sciences Research Science and Innovation at Cancer Research UK

Because of slow & variable study set-up timelines, the number of participants recruited to industry clinical trials fell by 44% between 2017/18 & 2021/22. As a result, the number of industry clinical trials initiated in the UK per year has fallen by 41% between 2017 and 2021.

Great work by the Eden2020 team 👏👏

Review on medical devices for delivering effective treatments for glioblastoma doi.org/10.3390/cancer… Imperial

This sounds like a great resource ⬇️

A great opportunity to help shape the next round of funding for the Cancer Grand Challenges scheme. 'Whether you're a researcher, clinician, supporter, funder or person affected by cancer, you can have your say.' Deadline 28th November. cancergrandchallenges.org/Challenge-Cons…

Excited to share that our #gbm trial is underway and 3 patients have been treated with our novel, non-invasive #SDT therapy! Thanks to our partners, we are changing the landscape of #braincancer treatment. Learn more at prn.to/3tjAwBS

UCL Brain Cancer Seminar Series. On Weds 7th Dec, presentations include Nir Lipsman - Focused Ultrasound in Neuro-Oncology: Early Experience in Human Trials. Register here: eventbrite.co.uk/e/ucl-brain-ca… UCL Biomedical Ultrasound Group University of Toronto Neurosurgery Focused Ultrasound Foundation Maya Thanou

Investigator Webinar: Enhance your Chance of Success with NIHR HTA Funding Thu, 17 November 2022, 16:00 – 17:00 GMT eventbrite.co.uk/e/investigator… National Institute for Health and Care Research @NIHR_RDSEM

News: #ClinicalTrial of Sonodynamic Therapy for #Glioblastoma Begins in Milan The study, led by Francesco Prada, MD of the Carlo Besta Neurological Institute, will use INSIGHTEC's #focusedultrasound device & is funded by the Focused Ultrasound Foundation. bit.ly/3XezwfS

BNOS Neuro-Oncology Dragons' Den. More info here: bnos.org.uk/wp-content/upl…

.Oncotelic Therapeutics (OTCQB: OTLC) has submitted a protocol to the FDA for a Phase 1 Trial for OT-101 (a transforming growth factor beta 2 inhibitor) as a treatment for paediatric patients with recurrent/relapsed DMG. The drug would be administered via the cerebral spinal fluid. oncotelic.irpass.com/Oncotelic-Init…

Exciting early phase study using convection-enhanced delivery to get treatment to the site of glioblastomas within the brain ⬇️

Last few days to add your voice to this ⬇️

Great to hear 👏👏

In this newsletter: Precision Medicine NICONeuroCorp, treating brain tumours with poliovirus Duke University, Dragons' Den & future BNOS conferences BNOS, Cancer Trial Finder ECMC Network (@ecmc-uk.bsky.social) Science and Innovation at Cancer Research UK, job opportunity with Dr. Sadhana Jackson, MD, and more - bit.ly/CBTDDCJan2023n…

Check out our review paper 'Childhood Brain Tumors: A Review of Strategies to Translate CNS Drug Delivery to Clinical Trials. Thanks to all contributors 👏👏Ruman Rahman @WillGBSingleton John Boockvar Lukas Faltings Miguel Oliveira Research at Children with Cancer UK mdpi.com/2072-6694/15/3…

In response to our community highlighting 'difficulty navigating the regulatory landscape' as a major challenge to clinical translation, we have produced a roadmap document that we hope will help: cbtddc.org/documents/road… @CRUKCamPaeds Edinburgh Cancer Research Research at Children with Cancer UK Ruman Rahman