Beyond happy to share our immuneML platform, which streamlines your machine learning analyses on adaptive immune receptor repertoire data. It can be extended in all possible ways. Fantastic teamwork with the Geir Kjetil Sandve lab. Let us know what you think! airr_community 1/2

Direct link to the immuneML preprint: biorxiv.org/content/10.110… 😇💻🎉.

Thrilled to be giving a seminar on adaptive immune receptor data analysis in the airr_community and The Antibody Society Webinar Series. Sign-up link: antibodysociety.org/learningcenter… Tuesday April 6, 2021 8:00 – 10:00 PT/11:00 – 1:00 ET/5:00 – 7:00 CET

Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day next Friday (3/26). All talks will be live-streamed (no registration required) at satijalab.org/scgd21/

Over the moon that our study on the predictability of antibody-antigen binding is featured on the cover page of Cell Reports! The cover was designed by our resident scientific illustrator 🧍‍♂️ (who's also the first author). Link to paper: cell.com/cell-reports/f…

Our lab is growing even more! We are looking to fill an immediate postdoctoral fellow position in the lab. The project will involve COVID-19 research (immunology and vaccines). Recent graduates with a background in virology or immunology should email or DM me if interested.

If you want to do a postdoc in experimental or computational immunology in the context of adaptive immune receptors, vaccines, and machine learning, get in touch with us by April 5, 2021. All details below.

My airr_community/The Antibody Society webinar on immune receptor (BCR, TCR) data analysis is now available on-demand for free (including the slides and written answers to all webinar questions; also those we did not have time to answer during the webinar): antibodysociety.org/learningcenter…

Great work led by 🧍‍♂️ Philippe A. Robert and Milena Pavlović, and wonderful collaboration with Geir Kjetil Sandve lab.

Congrats to Corey Watson, Steve Bosinger and the Smith Lab team on our newly awarded R24! So much more (rhesus) #ighgenomics on PacBio coming your way!!

GABA-derived drugs #gabapentin and #pregabalin bind to the same motif in human α2δ proteins that binds natural GABA ligands in bacterial chemoreceptors. This is a universal amino acid binding motif conserved throughout the Tree of Life: biorxiv.org/content/10.110…

The complete sequence of a human genome biorxiv.org/cgi/content/sh… #biorxiv_genomic

Special focus on COVID-19 and computational immunology. Please spread the word in your network. Check it out here: journals.elsevier.com/immunoinformat…

We used scRNA-seq + BCR data to show that patients with mild COVID-19 had increased frequencies of clonally-diverse, hypermutated memory B cells compared to patients with severe COVID-19 ~1 mo post-symptom onset. Steven Kleinstein 🖥 #Bcells #COVID19 jimmunol.org/content/early/…

Very happy that the 2nd paper from our collab with the Ballerini and Andreas Lossius labs is out today sciencedirect.com/science/articl…. We investigated TCR diversity in MS across CSF, brain, and peripheral blood. This work was co-led by Roberta Amoriello and Maria Chernigovskaya.

Congratssss! Beautiful work! Thanks so much for involving us! 🙏🥳🎉

1/3 Our paper introducing Immune2vec is out. shorturl.at/npX05 Immune2vec, is an adaptation of word2vec embedding technique for BCR sequences and repertoires.

We just released CompAIRR – a tool that reduces greatly the longstanding computational bottleneck of identifying shared identical and similar sequences among large sets of immune repertoires. All the details/links are in the thread below. Feedback is very welcome! airr_community

We’re thrilled to finally share the integrated Human Lung Cell Atlas (HLCA), a single-cell reference atlas of 444 individuals, and 2.2M cells! biorxiv.org/content/10.110… Human Cell Atlas Here’s a tweetorial on how we built it, and, most importantly, how you can use it: (1/20)

1/ Absolutely thrilled to announce the publication of our research on modulation of type I interferon in rhesus macaques! Our work was accomplished through close collaboration with the Mirko Paiardini and has now been featured in Science Immunology. science.org/doi/10.1126/sc…