itziar larrode leciñ (@itziarlarrodele) 's Twitter Profile
itziar larrode leciñ

@itziarlarrodele

Farmacéutica HUMS, Zaragoza.

ID: 619880269

calendar_today27-06-2012 10:35:01

3,3K Tweet

521 Followers

396 Following

GELTAMO (@geltamo) 's Twitter Profile Photo

Time of Day of CAR T-Cell Infusion and Outcomes in Large B-Cell Lymphoma | Blood | American Society of Hematology ashpublications.org/blood/article/…

Oncology Brothers (@oncbrothers) 's Twitter Profile Photo

Leukemia highlights from #ASH25 w/ @GCC_Cortes: ✅ #PARADIGM ✅ Venetoclax dosing schedule ✅ #KOMET007 ✅ #ASC4First Full Discussion: ⭐️ oncbrothers.com/leukemia-ash25 ⭐️ Also on the “Oncology Brothers” podcast #HemeTwitter #MedTwitter OncUpdates

GELTAMO (@geltamo) 's Twitter Profile Photo

Impact of Prior Bendamustine Exposure on Bispecific Antibody Outcomes in Relapsed/Refractory Follicular Lymphoma | Blood Advances | American Society of Hematology ashpublications.org/bloodadvances/…

PETHEMA (@_pethema) 's Twitter Profile Photo

The Lancet Haematology doi.org/10.1016/S2352-… publica 8-2025 los resultados del ensayo fase 3 GEM-2017FIT del #GEMPETHEMA. Los esquemas KRd y D-KRd logran mayor negatividad de EMR que VMP–Rd en pacientes mayores con mieloma múltiple no candidatos a trasplante. #MielomaMúltiple

The Lancet Haematology doi.org/10.1016/S2352-… publica 8-2025 los resultados del ensayo fase 3 GEM-2017FIT del #GEMPETHEMA. 
Los esquemas KRd y D-KRd logran mayor negatividad de EMR que VMP–Rd en pacientes mayores con mieloma múltiple no candidatos a trasplante. 
#MielomaMúltiple
GELTAMO (@geltamo) 's Twitter Profile Photo

Systematic review and meta-analysis: CAR-T vs bispecific antibody as third or later-line therapy for follicular lymphoma | Blood Cancer Journal nature.com/articles/s4140…

Dr. Chokri Ben Lamine (@abouabdrahman0) 's Twitter Profile Photo

Infectious complications post Azacitidine + Venetoclax (Aza-Ven) 🦠💉 🧬 Why infections are common? 👉 Profound & prolonged neutropenia 👉 Functional immune suppression 👉 Older / unfit AML population 🔥 Most common infections 🦠 Bacterial (most frequent) Febrile neutropenia

Dr. Chokri Ben Lamine (@abouabdrahman0) 's Twitter Profile Photo

Pola-Glo-Fi (Polatuzumab + Glofitamab) for Follicular Lymphoma 🔬🧬 🧠 What is Pola-Glo? ⚙️ Polatuzumab vedotin (anti-CD79b ADC) ➕ Glofitamab (CD20×CD3 bispecific T-cell engager) 🎯 Dual targeting: B-cell kill + T-cell activation 👤 Where used? 🔁 Relapsed / Refractory

PETHEMA (@_pethema) 's Twitter Profile Photo

Publicación PETHEMA en Cancer (01/01/2025) Estudio del Registro PETHEMA en HMA-sAML (n=479) confirma: Pronóstico muy desfavorable Beneficio del trasplante alogénico en 1ª RC Urgente necesidad de nuevos ensayos clínicos doi.org/10.1002/cncr.3… #PETHEMA #AML #Investigación

Publicación PETHEMA en Cancer (01/01/2025) 
Estudio del Registro PETHEMA en HMA-sAML (n=479) confirma: 
Pronóstico muy desfavorable 
Beneficio del trasplante alogénico en 1ª RC 
Urgente necesidad de nuevos ensayos clínicos 
doi.org/10.1002/cncr.3… 
#PETHEMA #AML #Investigación
Dr. Chokri Ben Lamine (@abouabdrahman0) 's Twitter Profile Photo

🧬 aCML (MDS/MPN with Neutropenia) – Practical Management Algorithm ( stepwise, exam + clinic oriented) 🔍 Step 1: Risk Stratification – “Who is high risk?” 🧠 Use clinical + molecular risk factors 🎂 Age ≥67 years → +1 🩸 Hb <10 g/dL → +1 🧪 TET2 mutation → +1 📊 Low

🧬 aCML (MDS/MPN with Neutropenia) – Practical Management Algorithm
 ( stepwise, exam + clinic oriented)
🔍 Step 1: Risk Stratification – “Who is high risk?”
🧠 Use clinical + molecular risk factors

🎂 Age ≥67 years → +1
🩸 Hb &lt;10 g/dL → +1

🧪 TET2 mutation → +1

📊 Low
GELTAMO (@geltamo) 's Twitter Profile Photo

Chimeric antigen receptor T-cell therapy and bispecific antibody sequence for large B-cell lymphoma: a systematic review and meta-analysis - The Lancet Haematology thelancet.com/journals/lanha…

Ahmed Kotb (@ahmedko45911157) 's Twitter Profile Photo

MDACC Algorithm for Ph+ ALL 🩸 🔹 Upfront: Ponatinib + Blinatumomab (+ HD MTX/Ara-C ×2 if WBC ≥70K) ➡️ MRD by NGS guides decisions • MRD− → Maintenance TKI • MRD+ → CAR-T →   – MRD− → Maintenance   – MRD+ → SCT Risk-adapted, MRD-driven strategy 👌 #POSS26

MDACC Algorithm for Ph+ ALL 🩸

🔹 Upfront: Ponatinib + Blinatumomab
(+ HD MTX/Ara-C ×2 if WBC ≥70K)

➡️ MRD by NGS guides decisions

• MRD− → Maintenance TKI
• MRD+ → CAR-T →
  – MRD− → Maintenance
  – MRD+ → SCT

Risk-adapted, MRD-driven strategy 👌

#POSS26
Ahmed Kotb (@ahmedko45911157) 's Twitter Profile Photo

AML Therapeutic Timeline🧬 •1970–2000s: 7+3backbone ± •2017 :Targeted era begins  –FLT3(midostaurin, gilteritinib, quizartinib)  –IDH1/2(ivosidenib, enasidenib)  –CPX-351 for AML-MR  –Venetoclax + HMA/LDAC for unfit/older • 2024–2025: Menin inhibitors (revumenib, ziftomenib)

AML Therapeutic Timeline🧬

•1970–2000s: 7+3backbone ± 
•2017 :Targeted era begins
 –FLT3(midostaurin, gilteritinib, quizartinib)
 –IDH1/2(ivosidenib, enasidenib)
 –CPX-351 for AML-MR
 –Venetoclax + HMA/LDAC for unfit/older
• 2024–2025: Menin inhibitors (revumenib, ziftomenib)
Papa Heme (@papa_heme) 's Twitter Profile Photo

Targeted therapies in AML. So many! FLT3 mutation = gilteritinib, midostaurin, quizartinib IDH1 mutation = ivosidenib, olutasidenib IDH2 mutation = enasidenib KMT2A rearrangement = revumenib NPM1 mutatuion = revumenib, ziftomenib CD33 = gemtuzumab ozogamicin BCL2 = venetoclax

Targeted therapies in AML.  So many!

FLT3 mutation = gilteritinib, midostaurin, quizartinib
IDH1 mutation = ivosidenib, olutasidenib
IDH2 mutation = enasidenib
KMT2A rearrangement = revumenib
NPM1 mutatuion = revumenib, ziftomenib
CD33 = gemtuzumab ozogamicin
BCL2 = venetoclax
S.E.F.H (@sefh_) 's Twitter Profile Photo

🆕🧬💉 Nueva evidencia en práctica clínica real sobre farmacogenética y cáncer de mama triple negativo metastásico Un estudio multicéntrico nacional promovido por la S.E.F.H analiza el impacto del polimorfismo #UGT1A1 en la seguridad y efectividad de un fármaco empleado en este

🆕🧬💉 Nueva evidencia en práctica clínica real sobre farmacogenética y cáncer de mama triple negativo metastásico

Un estudio multicéntrico nacional promovido por la <a href="/sefh_/">S.E.F.H</a> analiza el impacto del polimorfismo #UGT1A1 en la seguridad y efectividad de un fármaco empleado en este
Haematologica (@haematologica) 's Twitter Profile Photo

Do you know how to identify patients with acute myeloid leukemia who may have resistant disease after standard induction chemotherapy? The LSC17 score will help you. Don’t miss the news. haematologica.org/article/view/1…

Do you know how to identify patients with acute myeloid leukemia who may have resistant disease after standard induction chemotherapy? The LSC17 score will help you. Don’t miss the news.
haematologica.org/article/view/1…