The HertieNeuroscience Network Symposium takes place in Hamburg next week! We are very much looking forward to great scientific discussions and networking activities! Charité - Universitätsmedizin Berlin Uniklinik Bonn UKE Hamburg Universitätsmedizin Mannheim @LMU_Uniklinikum Hertie-Zentrum für Neurologie Universitätsmedizin Mannheim Universitätsklinikum Heidelberg

PREPRINT! Vagus nerve inflammation contributes to dysautonomia in COVID-19. Using mRNA sequencing and histopathology we identified strong interferon responses in vagus nerves possibly contributing to dysautonomia in COVID-19... medrxiv.org/content/10.110…

Check out our new manuscript looking at vagus nerve inflammation in COVID-19! Thanks to all colleagues who made this work possible Christina Mayer Lukas Bal INIMS Manuel Friese UKE Hamburg link.springer.com/article/10.100…

Check out our new manuscript about the longitudinal and multimodal assessment of the visual system in primary progressive #MultipleSclerosis INIMS Jens Kuhle Manuel Friese, spearheaded by J.P. Stellmann jnnp.bmj.com/content/early/…

Check out our new publication about health behaviors of a clinical cohort of persons with MS which emphasizes the need for education and assistance for behavior change in this population. frontiersin.org/articles/10.33…

Check out our new manuscript describing ATP-dependent calcium dynamics in dendritic cells in Science Advances. This was an amazing team effort, congratulations to all co-authors! 🍾 Looking forward to the next one! INIMS Vargas Lab science.org/doi/10.1126/sc…

Thank you Else Kröner-Fresenius-Stiftung for funding my research about #interferon signalling in the CNS and neuronal immune responses. Exciting research is coming! #StopNeurodegeneration #MultipleSclerosis #Neuroimmunology INIMS UKE Hamburg

NEW Research: 'Internet-delivered cognitive behavioural therapy programme to reduce depressive symptoms in patients with #MultipleSclerosis: a multicentre, randomised, controlled, phase 3 trial'. buff.ly/46qNIpZ

Our latest review is on important advances in the understanding of cerebral malaria and how these mechanistic insights could be translated into new therapies. @hadjilaou INIMS Manuel Friese @BNITM_de Thomas Jacobs, Ph.D. go.nature.com/46HKCyE

Check out our new manuscript about the practicability and acceptability of levidex, a digital health application designed to facilitate health behaviour change in pwMS bmcneurol.biomedcentral.com/articles/10.11…

In a great team effort we established recommendations for future mechanistic exercise studies in MS Michelle Ploughman @HvidLars @P__Zimmer Manuel Friese INIMS doi.org/10.1177/135245…

The Moving Exercise Research in #MultipleSclerosis Forward #MoxFo initiative: Exercise might exert immunomodulatory effects in MS: What do we need from mechanistic studies? Research from Sina Rosenkranz Manuel Friese INIMS UKE Hamburg ▶️ journals.sagepub.com/doi/full/10.11…

Check out our new publication in Sci Adv, in which we profiled inflamed neurons for their miRNA-mRNA network. We describe a valuable resource and a new resilience mechanism. INIMS⁩ ⁦⁦Iris Winkler⁩ @olepless ⁦⁦Merkler lab⁩ science.org/doi/10.1126/sc…

A constructed, neuron-specific microRNA–#mRNA network has identified an miR-92a–Cpeb3 axis that protects neurons from the degenerative effects of #neuroinflammation. INIMS Iris Winkler Manuel Friese Learn more: scim.ag/4XZ

Here we report the first MS patients treated with CD19-targeted CAR T cells. Acceptable safety with reduction in oligoclonal bands. Clinical trials will follow! UKE Hamburg INIMS @lk_pfeffer cell.com/med/fulltext/S…

Neurodegeneration in multiple sclerosis remains unresolved and without treatment. In our new review we untangled the current knowledge about the molecular pathways to identify the most promising leads. Marcel Seungsu Woo Jan Broder Engler INIMS nature.com/articles/s4158…

Proud to present our findings in Cell about neuronal STING as integrator of inflammatory and glutamate signals in #multiplesclerosis. Great work by Marcel Seungsu Woo , Christina Mayer , INIMS collaborators Merkler lab The Conrad Lab Markus Glatzel cell.com/cell/fulltext/…

How das chronic hyperexcitability contribute to #neurodegeneration in #MS? Check out our journey published now in Journal of Clinical Investigation with the incredibly talented Lukas Bal 🎓 from the INIMS Manuel Friese 🎉🔥 jci.org/articles/view/…

Out now: How does inflammation impact hyperexcitability and metabolism in neurons during #multiplesclerosis. Again great collaboration Merkler lab Markus Glatzel and others! Spearheaded by the MDs Marcel Seungsu Woo Lukas Bal jci.org/articles/view/…

We are hiring (2 positions) one Postdoctoral fellow and one Clinician-Scientist (all genders) in neuroimmunological research | Universitätsklinikum Hamburg-Eppendorf uke.jobs/index.php?ac=j… uke.jobs/index.php?ac=j…