Fireside chat at Sequoia Ascent 2026 from a ~week ago. Some highlights: The first theme I tried to push on is that LLMs are about a lot more than just speeding up what existed before (e.g. coding). Three examples of new horizons: 1. menugen: an app that can be fully engulfed by

This is the the quote I've been citing a lot recently.

Agents make ugly UIs because they've never seen good design. We've been fixing that, 2,000 DESIGN.md files from the world's best products, structured for a model to read and learn. Colors, type, spacing, layouts and more. Free. styles.refero.design

Researchers at Mayo Clinic have developed an AI model capable of detecting pancreatic cancer on routine abdominal CT scans up to three years before a clinical diagnosis is typically made. The model is trained to identify "invisible" signatures subtle structural changes in the

Try it out!

Grok 4.3

This guy literally built an ENTIRE operating system with Claude Code 🤯 now he is showing you exactly how. he dropped a 2+ hour masterclass *AND* a guide on the frameworks and included a free GitHub repo to get you coding right away. you seriously need to check this out 👇

Neuralink

Try the Grok Imagine agent mode beta!

Grok's Agent Mode just collapsed an entire creative workflow into a single canvas. Brainstorm. Write. Generate images. Edit. Produce video. All in one place. 74 seconds of demo and it makes half your creative app stack look redundant.

ANTHROPIC JUST EXPOSED HOW BADLY MOST PEOPLE ARE PROMPTING CLAUDE. Their applied AI team dropped a 24 minute workshop. Free. From the people who wrote the model. Not a course creator. Not someone who figured it out by accident. THE TEAM THAT BUILT THE THING. Here is what

We implemented Andrej Karpathy 's MicroGPT fully on FPGA fabric. No GPU. No PyTorch. No CPU inference loop. Just a transformer burned into hardware, generating 50,000+ tokens/sec. The model is small, but the idea is not: inference does not have to live only in software 👇

F.03 can now walk up/down stairs purely using it's onboard camera perception Our robots now walk from manufacturing when built to HQ This is trained end-to-end with reinforcement learning in simulation

UBTech Robotics has showcased its humanoid robot Walker S2 playing tennis with a human. Using real-time vision sensors, it tracks the ball, adjusts its position, and returns shots with good accuracy. The robot can also swap its own batteries, allowing it to operate continuously

The next chapter of space computing is here 🛰️ NVIDIA and its ecosystem are advancing AI from Earth-to-space across: ✔️ Earth Orbit and Infrared Imagery ✔️ Radio Frequency and Synthetic Aperture Radar ✔️ Autonomous Space Operations Leading commercial space companies and

OpenClaw = the employee. Hermes = the memory. Paperclip = the company. That’s the simplest way to understand the craziest open-source AI agent stack right now. Most people are still using 1 chatbot. This setup runs like an AI business.

🚨 SOMEONE JUST KILLED THE COACHING INDUSTRY a developer spent 22,000 hours building a Personal AI Operating System on top of Claude Code now anyone with a terminal can install it for FREE it knows your goals, remembers every decision you've made, and prepares your morning