It's been so great to see this amazing story develop, and now see it shared with the world! Congrats Ben, Eileen, Christy, and Karen!!

Does Pol II pausing control cell differentiation? Danya Martell Smart, in collaboration with Vijay Sankaran, studied Pol II pausing and SPT5 in human erythropoiesis and found Pol II pausing temporally coordinates cell cycle progression and erythroid differentiation. medrxiv.org/content/10.110…

🚨For my brand new lab in Utrecht (Faculty of Science, Utrecht University), I'm recruiting a Research Technician for 8 months! 🚨 Find more info here: tinyurl.com/2cu2kszd I deeply care about the development and success of the people in my lab, and think this can be a great training opportunity.

I am so excited to host Annie Vogel Ciernia for next week's FragileNucleosome seminar - Epigenetic Regulation of Microglial Immune Memory Annie's lab @ UBC-BMB-GSA studies how genes are regulated during brain development and in neurodevelopmental disorders. Link: harvard.zoom.us/webinar/regist…

I'm so proud of Claudia Mimoso for publishing this beautiful paper! She's put in a tremendous amount of work, both generating a crazy number of high-quality data sets and then analyzing the hell out of them. It has yielded really cool new insights into RNAPII elongation!

🚨New Epigenetics Conference Alert!🚨 Save the dates Oct 2-4 2023 for Signaling through chromatin: from molecules to ecosystems, in Grenoble, FRANCE. epigenetics.fr/sympo/ 20 outstanding speakers. 20 talks to be selected from abstracts. Why not you? Registration opening soon!

Unlocking the mystery of tRNA gene regulation! Our latest pre-print reveals a new protein and new mechanism promoting RNAPIII eviction and tuning metabolic responses. Read more now! doi.org/10.1101/2023.0… #tRNA #GeneRegulation #Fpt1 #RNAPIII

Our lab has a postdoc position available! Several possible projects in functional genomics of gene regulation, using exciting new approaches. Computional, wet-lab or both. If you are interested: contact us at [email protected].

Here's my PhD work! I found a link between CpG island turnover and the evolution of mammalian enhancers. Tweetorial coming soon! biorxiv.org/cgi/content/sh…

Where transcription begins determines where it ends! Check out our latest study, published today in Cell. A huge tour de force, led by the extraordinary Carlos Alfonso-Gonzalez @extended_gene doi.org/10.1016/j.cell… 🧵1/10

DOT1L promotes spermatid differentiation by regulating expression of genes required for histone-to-protamine replacement Read the full Research Article by Aashiq, Shannon R. Rainsford, Zachary D. Smith and Bluma Lesch Yale Department of Genetics: journals.biologists.com/dev/article/15…

We're excited to announce a special #FragileNucleosome mini-symposium! Join us on June 7th, from 8:30-11 AM PDT, to hear all about chromatin and transcription from 5 awesome scientists! Register here: harvard.zoom.us/webinar/regist…

💢Job alert - faculty position 💢 Are you an enthusiastic and creative scientist with computational research interests in the areas of health and disease? Radboud University at historic Nijmegen is a great place to be! Come join us! RT = nice Apply 👇 ru.nl/en/working-at/…

We are super excited for next week's seminar (June 21st 9AM PDT) featuring Alex Stutzman and Richard Adeyemi. Registeration link: harvard.zoom.us/webinar/regist…

Claudia Mimoso (Claudia Mimoso): "U1 snRNP increases RNA Pol II elongation rate to enable synthesis of long genes" youtu.be/KYUtk5990-I

I came to this country 15 years ago, and it is unbelievable to me that we haven't managed to improve this system even an iota in these years. It is not just a cruel system, it is also self-defeating. Please read this thread and tag your senators. Alex Padilla Senator Dianne Feinstein

Join us this Wednesday, August 16th, at 9AM PDT/12PM EDT, for our next seminar! We'll hear all about chromatin remodeling and genome access from Benjamin Patty (Sarah Hainer) and Ralph Grand! Register here: harvard.zoom.us/webinar/regist…

The Hubrecht Institute has openings for junior and senior group leaders. It's open to any discipline in life sciences. The Hubrecht is truly one of the best places in the world to start your lab, so apply! hubrecht.eu/job/tenure-tra…