Holly Pederson MD (@holly_pederson) 's Twitter Profile
Holly Pederson MD

@holly_pederson

Associate Professor of Medicine. Medical Director, Cleveland Clinic Breast Center. Special interest in Hereditary Risk.

ID: 3386063176

calendar_today21-07-2015 15:53:30

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Holly Pederson MD (@holly_pederson) 's Twitter Profile Photo
Holly Pederson MD
@holly_pederson

2 years ago

There are 70 intermediate risk BRCA2 Variants (missense variants with an OR of 2.85 found adjacent to the DNA binding region of the gene where the pathogenic variants are found. These “hypomorphic variants” may have partial function and are responsive to PARPI.