Hira Mian (@hirasmian) 's Twitter Profile
Hira Mian

@hirasmian

Multiple Myeloma Lead, Juravinski Cancer Centre, Hamilton Health Sciences, Dofasco Chair in Cancer Therapeutics, Associate Professor, McMaster University

ID: 419595308

calendar_today23-11-2011 15:03:26

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Hira Mian (@hirasmian) 's Twitter Profile Photo

Thank you everyone for making #IMS25 a huge success. Thank you Myeloma Society for hosting in Toronto. Wonderful science, wonderful presentations and wonderful colleagues from across the world Looking forward to #IMS26 Gordon Cook

Mostafa Faisal (@mostafafaisal14) 's Twitter Profile Photo

The endogenous T cell landscape is reshaped by CAR-T cell therapy and predicts treatment response in multiple myeloma Leukemia Journal nature.com/articles/s4137…

Ben Derman (@bdermanmd) 's Twitter Profile Photo

IFM2017-03: Dara-R (with dex for cycles 1-2 only) vs Rd for frail older adults. No surprise here: Dara-R > Rd, but there's more to it! 🕐The median age in this trial was 81! 👵All patients had IFM frailty score>=2 ! ➡️Nearly every subgroup statistically benefitted from

IFM2017-03: Dara-R (with dex for cycles 1-2 only) vs Rd for frail older adults. 
No surprise here: Dara-R > Rd, but there's more to it! 
🕐The median age in this trial was 81! 
👵All patients had IFM frailty score>=2 ! 
➡️Nearly every subgroup statistically benefitted from
Blood Cancers Today (@blood_cancers) 's Twitter Profile Photo

Cevostamab combined with pomalidomide and dexamethasone showed encouraging responses and safety for relapsed or refractory multiple #myeloma. Read more from a dose-expansion arm of the CAMMA 1 study presented by Hira Mian, of McMaster University, at #IMS25. 📖 buff.ly/aarWyyA

Cevostamab combined with pomalidomide and dexamethasone showed encouraging responses and safety for relapsed or refractory multiple #myeloma.

Read more from a dose-expansion arm of the CAMMA 1 study presented by <a href="/HiraSMian/">Hira Mian</a>, of <a href="/McMasterU/">McMaster University</a>, at #IMS25.

📖 buff.ly/aarWyyA
Vincent Rajkumar (@vincentrk) 's Twitter Profile Photo

MRD negative in myeloma requires a complete response (CR), including no detectable monoclonal protein. That’s the IMWG criteria. Criteria are not meant to be perfect. Experts will always disagree on some aspect. If everyone uses their own criteria we cannot interpret studies.

Robert Z. Orlowski (@myeloma_doc) 's Twitter Profile Photo

#Myeloma Paper of the Day: SEMA4A expression is hi where BCMA density is low; its deletion limits myeloma cell growth, migration, tissue infiltration, & osteoclast formation; CAR T cells show superior efficacy vs. BCMA CAR T in pre-clinical models: pubmed.ncbi.nlm.nih.gov/41072416/. #mmsm

#Myeloma Paper of the Day: SEMA4A expression is hi where BCMA density is low; its deletion limits myeloma cell growth, migration, tissue infiltration, &amp; osteoclast formation; CAR T cells show superior efficacy vs. BCMA CAR T in pre-clinical models: pubmed.ncbi.nlm.nih.gov/41072416/. #mmsm
Al Garfall (@algarfall) 's Twitter Profile Photo

TECVAYLI® plus DARZALEX FASPRO® combination regimen significantly improves progression-free survival and overall survival versus standard of care jnj.com/media-center/p…

Raghu Venugopal MD (@raghu_venugopal) 's Twitter Profile Photo

Toronto's University Health Network raised $30 million for Canada Leads to attract the best scientists. 25 are recruited and 75 more will be finalized. As the U.S. implodes - Canada steps up. Key reporting by Avis Favaro on Brad Wouters 🇨🇦 University Health Network UHN Foundation Dr. Kevin Smith

Toronto's University Health Network raised $30 million for Canada Leads to attract the best scientists. 

25 are recruited and 75 more will be finalized. As the U.S. implodes - Canada steps up. 

Key reporting by <a href="/Avis_Favaro/">Avis Favaro</a> on <a href="/bradwouters/">Brad Wouters 🇨🇦</a> <a href="/UHN/">University Health Network</a> <a href="/uhnfoundation/">UHN Foundation</a> <a href="/KevinSmithUHN/">Dr. Kevin Smith</a>
Juanjo Garcés (@juanjogrcs) 's Twitter Profile Photo

Another big hit for #CTCs in #mmsm, this time by the Rotterdam group (Erasmus MC Intl). Beautiful and very important study! Congrants, Luca Bertamini and the rest of the team! ashpublications.org/blood/article/…

Another big hit for #CTCs in #mmsm, this time by the Rotterdam group (<a href="/erasmusmcintl/">Erasmus MC Intl</a>). Beautiful and very important study! 
Congrants, <a href="/LucaBertamini/">Luca Bertamini</a> and the rest of the team!
ashpublications.org/blood/article/…
Ben Derman (@bdermanmd) 's Twitter Profile Photo

🚨Calling all myeloma clinicians! What diagnostics are you using to help with treatment decisions at diagnosis and relapse? Karyotype? FISH? NGS panels? We want to know! Fill out this quick (dare I say fun!) survey here: bit.ly/Guide-MM

VJHemOnc (@vjhemonc) 's Twitter Profile Photo

Next up at #iwHRMM25, Doris Hansen (Moffitt Cancer Center) will highlight the optimization of CAR T-cell therapy for high-risk #MultipleMyeloma.💉🩸 #MMSM #Myeloma #HemOnc #ImmunoOnc #CARTCell

Next up at #iwHRMM25, Doris Hansen (<a href="/MoffittNews/">Moffitt Cancer Center</a>) will highlight the optimization of CAR T-cell therapy for high-risk #MultipleMyeloma.💉🩸

#MMSM #Myeloma #HemOnc #ImmunoOnc #CARTCell