What a treat to write about a DNA nanoengine engineered by Mathias Centola, floppleton.bsky.social, Sujay Ray, Martin Centola, Robb Welty, Julian Valero, Nils Walter Lab, Petr Šulc & Michael Famulok in @naturenano nature.com/articles/s4156…

Proud of MSTP at Case Western Reserve University student Eshan King for publishing 1st thesis paper this week PLOS Comp Biol! In it, we explore how #FitnessSeascapes encode multple #evolutionary trade-offs during changing drug dosing (either in space or time). Short thread journals.plos.org/ploscompbiol/a…

Check out the latest research project led by Flynn Zhi and Andy Lininger! They've had a blast manipulating random lasing correlations in doped liquid crystals. CWRU Physics @nanoplasmc #OSA_OL opg.optica.org/ol/viewmedia.c… #Photonics #Innovation

How do bioenergetic costs of microRNAs depend on interaction strengths? Our work (now in PNAS) reveals an energetically optimal affinity range for microRNA-mRNA interactions (which coincides with 7 nucleotide complementarity!)-w/ @HinczewskiLab PNASNews #Bioenergetics #microRNA

Eshan is on a roll! New preprint from this future #physicianscientist MSTP at Case Western Reserve University biorxiv.org/content/10.110… Ever want to do some evolutionary simulations and need to know the death rate?? It’s a hard problem - made harder because most assays are blind to it… Thread -

Our paper with Jordi and Ricard Solé is out! We consider the problem of finding the nonequilibrium steady state that optimizes free energy harvesting + illustrate it on the amazing photosynthetic bacteriorhodopsin system. A long time in the making ...

Please RT. We are looking for a motivated PhD candidate to work on the biophysics of protein condensates with high-speed atomic force microscopy 👇🏾 Force microscopy group in collaboration with Mauro Modesti CRCM - Cancer Research Centre of Marseille @univamu @Insermpacacorse ANR - Agence nationale de la recherche euraxess.ec.europa.eu/jobs/202000

Excited to share the labs newest PNASNews publication Reinforcement learning informs optimal treatment strategies to limit antibiotic resistance from MSTP at Case Western Reserve University student (and CWRU systems biology graduate excellence award winner!) Davis Weaver & team 🧵 pnas.org/doi/10.1073/pn…

Check out our perspective paper on AI strategies for optimizing additive manufacturing in nanophotonics! #AI #AdditiveManufacturing #Nanophotonics

We propose that the well-known concept of colloidal diffusiophoresis can also be manifested in hydrogels, offering a way to speed up gel deformations (that can otherwise be really slooow). journals.aps.org/prl/abstract/1…

1/3: Paper Alert! How does chromatin phase segregation influence nuclear morphology in eukaryotic cells??? Many genetic diseases with dominant epigenetic alterations also show nuclear-scale changes in 3D genome organization accompanied by nuclear-shape abnormalities...

Excited to share new paper led by postdoc Jeff Maltas (on the job market!) out today in PRX Life (1/4 🧵) Frequency-Dependent Ecological Interactions Increase the Prevalence, and Shape the Distribution, of Preexisting Drug Resistance #cancer #ecology journals.aps.org/prxlife/abstra…

Incredibly excited that our paper examining the role of ecological interactions in preexisting drug resistance is out! We tackle the apparent paradox between the cost of resistance in the absence of treatment, and the ubiquity of preexistence. 1/20 Link: go.aps.org/4c5FmH4

So fun! PRX Life chose our work for their first cover! Congrats Jeff Maltas and team!

Thrilled to share our new paper published today in Nature Communications: "Motion blur microscopy: in vitro imaging of cell adhesion dynamics in whole blood flow" Motion Blur Microscopy (MBM) integrates microfluidics and light microscopy with #AI to provide a low cost, easy to implement

Is there more than one mechanism underlying resistance to an antifungal drug? How many mechanisms are there? Kara Schmidlin and Sam Apodaca explore these questions in their paper out today in final form at eLife - the journal! elifesciences.org/articles/94144 (1/9)

My colab with DeWeese Lab and Adri Zhong is out Physical Review E ! journals.aps.org/pre/abstract/1… Here we provide the theoretical foundation for stochastic normalizing flows and show how to efficiently sample free energies with counterdiabatic driving! Retweet and check it out!

Beautiful story of discovery #microRNA