Graeme Newton
@graemewtnewton
Genetics, Pain, RNAi, Pharma, Biotech. Bioinformatics and Data Science Consultant @ Newton Research. Tuba player in my spare time!
ID: 1395693266465665029
http://www.newtonresearch.co.uk 21-05-2021 10:49:54
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megabase When is a "pathogenic" variant in a classic pain gene (NaV1.7) not pathogenic? When its carried by many thousands of people and has no evidence of a pain phenotype or analgesic prescriptions. We need to reconsider how we assign pathogenicity to variants. medrxiv.org/content/10.110…