Working on (neuro)pharmacology of new synthetic opioids? Consider submitting to a Special Issue of #Neuropharmacology, “Advances in Opioid Neuropharmacology: Focus on Novel Synthetic Opioids (NSOs)”, guest edited by M. Baumann, Grant Glatfelter & @marthevdp. sciencedirect.com/journal/neurop…

Great news for all the busy 🐝🐝 involved in novel synthetic opioid #NSO (neuro)pharmacology research! ⏩ the submission deadline for a dedicated special issue in Neuropharmacology has been extended to Jan 1st, 2025. ✅ Looking forward to receiving your submissions!

Check out this review article the great Dave Nichols and I wrote on the "Chemistry/structural biology of psychedelic drugs and their receptor(s)". Online today! This is a big milestone as it represents the first independent publication from my lab! bpspubs.onlinelibrary.wiley.com/doi/epdf/10.11…

We are seeking individuals with Post Traumatic Stress Disorder who are at least 21 years of age to take part in a research study. This study will take place in Baltimore, MD and will investigate whether psilocybin can improve quality of life in those diagnosed with PTSD. Learn

The next generation of #nitazene analogues…?🔮 (1/3) ⏩ Our study dives into the harm potential of 15 “prophetic” nitazenes ⏩ Goal = to strengthen #preparedness & risk assessments 👏 Thx to a fabulous team incl Cayman Chemical, István Ujváry 🇭🇺 ⚗️ 📚 🖥️🏳️, Grant Glatfelter, M Baumann Designer Drug Research Unit

Just out #openaccess in Pharmacological Research: Marthe Vandeputte & a 💪 set of collaborators: 🔮 "Characterization of novel nitazene recreational drugs: Insights into their risk potential from in vitro µ-opioid receptor assays and in vivo behavioral studies in mice". sciencedirect.com/science/articl… 👇

Check out our new publication on the pharmacological characterization of novel, "prophetic" #nitazene synthetic #opioids - some of which were found to be more potent than #fentanyl Lead by the brilliant Marthe Vandeputte & Christophe Stove sciencedirect.com/science/articl…

New pub out now in ACSChemNeurosci comparing 5-HT1A & 5-HT2A activities of #5MeODMT analogs #psychedelics pubs.acs.org/doi/full/10.10…

🚨 Save the Date! 🚨 I’ll be speaking at the ISRPsychedelics virtual conference on March 7th! ✨ 24 presentations from psychedelic researchers. ✨ Cutting-edge insights in psychedelic science. ✨ Register here today - isrpsych.org/store #Psychedelics #ISRP2025

Congrats, Margarita!

Toxicological evaluation, postmortem case descriptions, and pharmacological activity of N,N-dimethylpentylone and related analogs doi.org/10.1093/jat/bk…

📣 The Early Warning Advisory reports a global ⬆️ in nitazenes, a potent synthetic opioid group. Since 2019, 26 variants surfaced in 30 countries, causing overdoses. Urgent action is needed: stronger collaboration, better detection, & health responses. 👉 bit.ly/3QnKmy4

Catch us tomorrow for the ISRPsychedelics virtual meeting! isrpsych.org/conferences

Excited to share a new preprint regarding the use of open-source machine learning-based toolkits to quantify the head-twitch response in mice. biorxiv.org/content/10.110… Many thanks to the coauthors that made this possible, especially our talented postbac, Zander!

Rapid, open-source, and automated quantification of the head twitch response in C57BL/6J mice using DeepLabCut and Simple Behavioral Analysis biorxiv.org/content/10.110… #psychedelics #bufotenine #headtwitchresponse #machinelearning #pharmacology

Comment: I've given both drugs to many patients without inducing a psychedelic experience with typical therapeutic doses.  hallucinations rare in my clinical experience and that of others who are neurologists although it does rare happen. #psychedelic pubmed.ncbi.nlm.nih.gov/40322975/

Out now: Psychedelic-like effects induced by DOI, LSD, and psilocybin in male and female C57BL/6J mice Check it out 👇 link.springer.com/article/10.100… #psychedelics #HTR

Our pub describing an approach to quantify the head twitch response in mice from video recordings using the open-source machine learning-based toolkits DeepLabCut and SimBA is out now in ACS Publications Bio & Med Chem Content Pharm Trans Sci pubs.acs.org/doi/full/10.10… #psychedelics #HTR #machinelearning

Fogarty et al. (incl. Barry K Logan 🇬🇧🏴󠁧󠁢󠁳󠁣󠁴󠁿🇺🇸🏴‍☠️, Donna Papsun, Alex J Krotulski, PhD, Grant Glatfelter) developed and validated an LC-MS/MS method for quantifying DMP & related cathinones, achieving chromatographic resolution of isomeric variants ⚠️. Read it all➡️bit.ly/3Ft0QDm

This manuscript was chosen as the NIDA IRP paper of the month 😎🙏🙌 irp.nida.nih.gov/featured-paper…