
Laurent Gapin
@gapinlaurent
Professor - Immunology - University of Colorado
ID: 1268672096277721089
04-06-2020 22:33:06
374 Tweet
179 Followers
129 Following



So excited and honored to be part of this group! Thanks to past and current lab members-love you! And to Stanley Maloy ᐯIᑕTOᖇ ᑎIᘔET @DMAronoff for nominating me! Representing CO w Horswill Lab 🏔️CU Anschutz Dept of Immunology & Microbiology asm.org/Press-Releases…

Selective engagement of Vγ9Vδ2-T and type 1 NKT cells using a CD1d-Vδ2 Bispecific T cell engagers results in robust antitumor activity and is well tolerated in NHPs Cell Reports Medicine cell.com/cell-reports-m…




Promiscuous recognition of MR1 by canonical MAIT TCRs endowed with dual reactivity to both microbial and self-antigens enables MAIT cell responses in the absence of microbial infection Journal of Experimental Medicine doi.org/10.1084/jem.20…

Chancellor, Simmons, De Libero University of Basel, Lepore et al. show that promiscuous recognition of MR1 by canonical MAIT TCRs endowed w/ dual reactivity to both microbial and self-antigens enables MAIT cell responses in the absence of microbial infection. bit.ly/3JEyJQe







In collaboration with the Meyer lab (Hannah Meyer ), latest work by Dr. Loh and Salome Carcy (@CarcySalome ) where we analyzed using single cell RNA-seq the transcriptional states of innate-like T cells (NKT, MAIT and GD) and conventional T cells in the human thymus and blood.

Happy to share new work from us on persisting impairment of #MAIT cells in people recovering after very severe #COVID19. These results suggest weakened antimicrobial #immunity in this patient group. journals.aai.org/jimmunol/artic… Karolinska Institutet Center for Infectious Medicine The Journal of Immunology

