Glad to share our recent paper on cys oxidation. We focused on 1) what makes some cys more susceptible to oxidation, 2) trends and recurring motifs observed of oxidized cys with other amino acids, 3) structural and dynamical consequences of cys oxidation. bit.ly/3Snzy2h

Which different roles in immune sensing and immune cell activation are taken by lipids? Böckmann Lab Lab in Erlangen has openings for #postdoc and #phd positions for #simulation studies on #immune #domains, #receptor - lipid interactions ImmunoDomains

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Computational fragment linking finds submicromolar inhibitor for underexplored SARS-CoV-2 protein NSP3. Ultra-large library docking reveals more scaffolds: practicalfragments.blogspot.com/2023/01/from-f… James Fraser (A$AP J) @BShoichet PNASNews Stefan Gahbauer Enamine Ltd 🇺🇦 Frank von Delft Adam Renslo

My preprint "bigger is better"with John Irwin Chemistry and @BShoichet is now published on Nature Chemical Biology. Check out our summary thread & full details rdcu.be/c3x36

I'm #hiring a Scientist to solve molecular mysteries in cell death and inflammation at Genentech. Best suited for talented protein biochemists interested in #cryoEM. Please RT! Apply here: careers.gene.com/us/en/job/GENE…

DOCK Blaster 2.0: Automatic optimization of a docking model using retrospective enrichment, available now in ChemRxiv for your comments doi.org/10.26434/chemr…

Super excited to share our recent collaborative work between @LabSkiniotis and Tall G protein Lab showing structures of Ric-8B complexed with Gαs and Gαolf sciencedirect.com/science/articl…

Cool new paper from @BShoichet and Bryan Roth !! biorxiv.org/content/10.110…

Docking for EP4R antagonists active against inflammatory pain discovers new analgesics! Bryan Roth @BShoichet Great work!! nature.com/articles/s4146…

Check out our recent paper in Nature Communications, co-authored by Enamine researchers: “Docking for EP4R antagonists active against inflammatory pain”. doi.org/10.1038/s41467… Visit bit.ly/3RCQtzW or bit.ly/4793wOl for more information on our products.

We are thrilled to present a new article co-authored by Dr. Yurii Moroz, detailing a groundbreaking study that focused on the prostaglandin E2 receptor 4 (EP4R) and discovered a new way to treat inflammatory pain. Follow the link to learn more tinyurl.com/yvvjjm2. #chemspace

Super cool tool and fun collaboration! Thanks and congrats Matteo Ferla!! 👏