Not at #ATS2024, but relevant. Hot off the press CHEST® Journal and open access! "Differential Effect of PEEP Strategies in ARDS Patients: A Bayesian Analysis of Clinical Subphenotypes" doi.org/10.1016/j.ches… Ary Serpa Neto

Incident #HeartFailure in #CKD : #proteomics informs biology and risk stratification 📍 2906 #CRIC participants, validated in ARIC. 📍P’ Outcome: 14-year incident #HF (390 events); S’ outcome : 4-year HF (183 events). 📍200+ linked to incident HF (P < 1 × 10⁻⁵); 17 remained

Atherosclerosis underlies 2/3 of cardiovascular disease (CVD)🫀🧠 This JACC Journals review proposes a precision medicine–based approach for personalized CVD prevention via subclinical athero detection with imaging 🖥️ and circulating biomarkers🩸 sciencedirect.com/science/articl…

Human Immunology of Heart Failure: Deconstructing Inflammatory Risk. academic.oup.com/eurheartj/adva… #immunology #HF #inflammation #risk European Society of Cardiology European Society of Cardiology Journals

2024 Heart Failure update has just been published in ESC Heart Failure. It's a long read, but worth the time :) doi.org/10.1002/ehf2.1… Marat Fudim, MD MHS Marco Metra European Society of Cardiology Cardiotweet Mateusz Sokolski Alexandre Mebazaa EJHF Editor-in-Chief

Predicted Deleterious Variants in Cardiomyopathy Genes Prognosticate Mortality and Composite Outcomes in the UK Biobank JACC Journals jacc.org/doi/abs/10.101….

Autoimmune inflammatory diseases and HFpEF We see more and more overlap in clinical practice. Potentially relevant to the peripheral/muscular impairments in O2 handling observed jacc.org/doi/10.1016/j.…

#OriginalResearch: Sacubitril/valsartan did not cause cognitive decline in patients with HFpEF as measured by the MMSE over up to 3 years of follow-up. University of Glasgow Heart Failure Research Group, Pardeep S Jhund #AHAJournals ahajournals.org/doi/10.1161/CI…

Mechanical circulatory support in severe cardiogenic shock: microaxial flow pumps for all?? Editorial focused on available evidence on the use of VA #ECMO & alternative #MCS Open access #FOAMcc #FOAMecmo on Critical Care 🔓 rdcu.be/dLt6T

Tremendous historical perspective and contemporary review of G-coupled protein receptors from H. Rockman, R. Lefkowitz, Sudarshan Rajagopal & colleagues. They continue to be among the top targets for CVD ahajournals.org/doi/full/10.11… Circulation Research Duke Heart Duke Cardiology

Nice work on inflammation on cardiovascular risk in JACC Journals! Important risk factor. More discussion and work needed on how to best address this jacc.org/doi/10.1016/j.…

🔥Fresh Press 🔥 We propose a novel candidate therapy for HFpEF. doi.org/10.1002/ejhf.3… Sanjiv J. Shah, MD Sheldon Litwin Kavita Sharma Mikhail Kosiborod Saint Luke's Mid America Heart Institute Saint Luke's

📌Global epidemiology of #HeartFailure Updated topic in Nature Reviews Cardiology #HF #Epidemiology #Statistics

Among 1142 Vanderbilt Health cath lab pts, ~1 in 5 have clonal hematopoiesis of indeterminate potential (CHIP). Those w/ CHIP vs w/o had 2.4-fold & 1.6-fold LM & LAD lesions, respectively ahajournals.org/doi/abs/10.116… Circulation: Genomic and Precision Medicine Brett Heimlich Alex Bick

Herzlichen Glückwunsch an die Universitätsmedizin Mainz zur Auszeichnung als Fortbildungsstandort Junge Kardiologie! 🎓❤️ #Kardiologie Philipp Lurz Franziska Koppe-Schmeißer 👉herzmedizin.de/fuer-aerzte-un…

Patients with #HFpEF and autoimmune or primary inflammatory disorders showed lower Ca-Vo2 at CPET, ⬆️ incidence of composite outcome (log-rank P=0.030) and a ⬆️ risk for HF hospitalization showing distinctive clinical subgroup characteristics. bit.ly/3zBBlfw #JACCHF

Cardiogenic shock: do we need a paradigm shift? The paradigm shift in the management of #CardiogenicShock: moving from pure mechanical left ventricular unloading to neurohumoral and anti-inflammatory blockade with or without LV mechanical assistance academic.oup.com/eurheartj/adva…

Genetic or pharmacological inhibition of IL-11, a pro-inflammatory and pro-fibrotic cytokine of the IL-6 family, has anti-aging effects expanding healthspan and lifespan in mice 👉an anti-IL-11 antibody is in early clinical trials for lung fibrosis 🔗nature.com/articles/s4158…

Our ascending aortic diameter estimation model incorporating clinical factors and genetics is now out in #EHJ European Society of Cardiology Journals

C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice biorxiv.org/cgi/content/sh… #biorxiv_immuno