H5N1 in waste water in USA

Important paper if you are interested in influenza and nanopore sequencing!

New paper alert! Learning how flu viruses spread through, and between, wild and domestic #bird populations improves preparedness for #HPAI. A recent introduction of H10 #virus lineage to Australia via wild birds subsequently spread to poultry and zoo birds academic.oup.com/ve/advance-art…

Brilliant resource: systematic review of laboratory investigations into the pathogenesis of avian influenza viruses in wild birds. Really happy to finally see this one in print! 👉royalsocietypublishing.org/doi/10.1098/rs… Resource: sciencebase.gov/catalog/item/6…

It was an honour to be invited earlier this week to visit the Roslin Institute and give a seminar on influenza virus reassortment. In addition, I enjoyed several meetings with experts in influenza virus research discussing ideas of potential collaboration.

I am thrilled to share this review on influenza A/H5N1 in dairy cows with colleagues in the USA and UK in mbio,  summarising the current situation , describing how the virus emerged, and provides recommendations better control strategies.  journals.asm.org/doi/10.1128/mb…

Review of origin, evolution and cross species transmission of HPAI H5N1 in dairy cattle. 👉journals.asm.org/doi/10.1128/mb…

In 2022-2023, H9N2 and 2321a H5N1 predominatnt in Bangladesh LBMs. Starting in 2023, emergence of 2344b HPAI - reassortants w 2344b and wild bird viruses. Will 2344b displace 2321a? 👉tandfonline.com/doi/full/10.10…

1/ Our recent publication is online. We show that a clade 2.3.4.4b H5N1 virus attaches to, and replicates more efficiently in human respiratory epithelium than a clade 2.3.2.1 H5N1 virus that circulated in 2005. biorxiv.org/content/10.110…

It is finally OUT!! After a pandemic, lab moving across the country!, 1+ under review and >120 panels later. 🧵 cell.com/molecular-cell…

What will viruses do next? 🦠 New article from Nature Communications explores how #AI is transforming viral evolution prediction. Research from Robertson uses AI models to better understand these vast evolutionary trajectories and determine their limits. nature.com/articles/d4158…

VIRUS-MVP: A framework for comprehensive surveillance of viral mutations and their functional impacts biorxiv.org/content/10.110… #biorxiv_bioinfo

Viral library w random mutations in the HA of H9N2, passaging in chickens/mice = selection of variants. wild type selected in chickens, variants with ΔL226/R229I selected in mice, N289D mutation (pref α2,6) selected in ferrets 👉journals.asm.org/doi/full/10.11…

More human cases by avian influenza H5N1

Reassortment is hard. Here, a compuational model incorporating AIV diversity. primary hosts contributing to reassortment in H5Nx viruses: domestic poultry in China, and wild birds in North America and Europe 👉journals.plos.org/ploscompbiol/a…

Easy pipeline to trace reassortment among influenza A viruses. Revealing Reassortment in Influenza A Viruses with TreeSort academic.oup.com/mbe/article/42…

Earlier this month, I had the opportunity to present two talks on zoonotic avian influenza viruses in Egypt and Southeast Asia (Bangladesh and Laos) at the WVPAC in Kuching, Malaysia. It was also a pleasure to meet my former professors, colleagues, and friends.

I am looking for a motivated PhD student to join my group at the University of Liverpool to study the interspecies transmission mechanism of avian influenza viruses, in collaboration with Uppsala University and the Pirbright institute. More info findaphd.com/phds/project/m…

Update from the WHO/WOAH/FAO H5 Evolution Working Group: 12 new clade designations based on division of clade 2.3.2.1c and 2.3.4.4 viruses, reported in Africa, Antarctica, Asia, Europe, the Middle East, the Americas and Oceania 👉biorxiv.org/content/10.110…

POSTDOCTORAL OPPORTUNITY: We are seeking a motivated Postdoctoral Researcher to join our team at Uppsala University, Sweden to work on exploring the mechanisms and barriers that govern interspecies transmission of influenza A viruses. More information uu.se/en/about-uu/jo…