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Hi all, very glad to announce our paper on “Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events” is now out nature.com/articles/s4146… in Nature Communications. summary in German here: x.com/HPI_DE/status/… twitter summary below. 1/6

Thanks @JelleVlaanderen for bringing our team at genomicstartu up to speed with #exposome research. Really look forward to integrating exposome data into Estonian Biobank 🌎expanseproject.eu theguardian.com/environment/ng…

Congratulations Doctor ⁦Kertu Liis Krigul⁩ 🥳 excellent work, beautiful presentation, brilliant scientist! 💙

Happy to share our most recent GWAS meta-analysis of 249 circulating metabolic biomarkers (Nightingale Health platform) in up to 619,372 individuals. medrxiv.org/content/10.110…

Now published! rdcu.be/dXTwC Congrats Mattia Cordioli Andrea Corbetta Hanna Maria Kariis and team

1/6 🚨 Thrilled to share our new preprint on the genetics of dermatophytosis susceptibility on medRxiv! 🚨 With over 250K cases and 1.37M controls across 4 cohorts, we uncover 30 loci that affect risk for this fungal infection affecting 20% of the global population. 🌍

🚨 Our preprint on parent-of-origin effects (POEs) is out! With our new method, we inferred the parental origin of >220,000 individuals, revealing new insights into the genetic architecture of complex traits. 👉 Read here: medrxiv.org/content/10.110… 👇 Highlights below!

In @Laboratorynews, I discuss the role of biobanks in revolutionising precision medicine. 🧬   I explain how the Estonian Biobank is using genomic insights to better understand the factors influencing public health and disease.   Read more, here 👉bit.ly/3ON6xNy   #Biobanks

🦠 Excited to share our new collection of human gut #archaea species! 🎉 🇪🇪From Estonian Biobank, we present a dataset of 144 strains across 21 species, including 9 entirely new species! A thread 🧵 #MAG #EstMB #TartuMicrobiome #microbiome #humangut

This is what happens when you return research results to biobank participants: ✅The 2nd most googled “How to…?” question in Estonia 2024: “How to become a biobank participant?” ✅"Estonian Biobank" among Top10 search terms. Huge thanks to all at Estonian Biobank & genomicstartu ✨

1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in Cell. cell.com/cell/fulltext/… A thread 🧵:

We are delighted to contribute with Estonian Biobank data to this massive collaboration 🎉 So glad to see this work published!

Delighted to accompany President Dr. Dr Mohamed Muizzu on his visit to the University of Tartu Institute of Molecular and Cell Biology, today. We were warmly welcomed by Professor Lili Milani, Head of Estonian Biobank & Professor of Pharmacogenomics and had an inspiring exchange on advancing

🧬🧠Recent research Estonian Biobank genomicstartu revealed that high genetic liability to #ADHD raises risks for 80 health conditions like #COPD (+70%), #obesity (+60%) & type 2 diabetes #T2D (+45%) - even without an ADHD diagnosis. Better screening & awareness for adults is needed!

New paper out: microbiome and causal inference! Let us tell you a bit more:

Tremendous work by Natàlia Pujol Gualdo Triin Laisk and team! 👏🏼👏🏼👏🏼

💡Can we use real world drug purchase data to study the genetics of medication dosing? We explored this by analyzing 20 years of digital drug dispensing data linked to the Estonian Biobank which hosts 212,000 genotyped participants. 🧵 📄 doi.org/10.1101/2025.0…

Excited to share our recently published overview of the Estonian Biobank 🧬 We highlight the unique features of the biobank and the conducted scientific research, including the many recall studies that have been carried out over the years: nature.com/articles/s4146…

A study in Nature Medicine provides a cross-trait atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses. go.nature.com/3YldiLt 🔒

🎉 Excited to share that our latest paper is now published! We investigated genetic factors linked to antidepressant side effects in 13,000 individuals from the Estonian Biobank, leveraging data from questionnaires and clinical notes using NLP. shorturl.at/3tAkg