Super excited to share that ENGRAM is out today! ENGRAM cells are programmed to write their histories into the genome, recording the intensity, duration, and order of biological events simultaneously. nature.com/articles/s4158…

Prospective power analysis is hilarious because your replace an arbitrary guess of sample size with an arbitrary guess of the effect size you’ve yet to measure, do a touch of arithmetic, and suddenly it’s considered rigorous

So much this! Can we please move to study designs that discuss exploratory data analysis, batch effects correction, etc that are more meaningful for high quality work

THIS!!!!!

Gloria al bravo pueblo!!! 🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪🇻🇪

Spent some of the weekend playing around with our new 10x Genomics Xenium 5K Plex data- look at how nicely these endothelial transcripts (PECAM1 and TIE2) map onto vessel structures. So excited to see where this data takes us! PS- this Xenium run was done by DanielaGrases

It's going to be a great meeting! Looking forward

VIVA VENEZUELA, CARAJO!

Freedom for #Venezuela

POSTDOC OPPORTUNITY TO JOIN US! Are you interested in how nuclear metabolism impacts on chromatin function and gene regulation in leukemia? Apply for an attractive postdoc position with us through the MSCA @carrerasleaders program! More info here: buschbecklab.org/join-us/

Eduard Porta In this paper we propose funding practices alternatives and discuss advantages/disadvantages. The current system is particularly harmful to ECRs sciencepolicyjournal.org/article_103812…

'Mechanisms that clear mutations drive field cancerization in mammary tissue' nature.com/articles/s4158…

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye! The dye is tartrazine, used in Doritos! science.org/doi/10.1126/sc…

The Severo Ochoa award is the highest recognition given to research institutes in Spain. It recognized the excellence of Josep Carreras Leukaemia Research Institute (IJC) achieved in the past 5 years and the ambitious plan for future improvement. A great honor and greater responsibility for us.

Couldn't agree more with this thread

🥳 Incredibly proud and excited to share our latest work Université de Lausanne CHUV / Centre hospitalier universitaire vaudois, now out in Nature Machine Intelligence! Led by the brilliant Pushpak Pati, we show how #GenerativeAI can be used to synthesize multiplexed IHC images for several markers from a single H&E image. Details 🧵👇:

'The evolutionary theory of cancer: challenges and potential solutions' nature.com/articles/s4156…

This is fantastic