Proud of Dr. Yi Chai, Yuqi, and Rachel's excellent work on the potential inverse association of antipsychotic use with lung cancer, supervised by myself and Prof Prof Ian Wong; findings now available in Communications Medicine #drugrepurposing rdcu.be/dm3ig

Proud of Dawn, my former RA, who led this excellent review article as 1st author; we found that among #SSRI RCTs, many did not consider #multimorbidity in their sample adequately: real-world evidence is crucial in monitoring drug safety & effectiveness! sciencedirect.com/science/articl…

My MMedSc/ RA supervisees HKU Pharmacy HKU Medicine The University of Hong Kong led and published our meta-analysis in Sleep Medicine Reviews (IF = 10.5; 11/212 in Clinical Neurology) showing increased fracture risks after sedative-hypnotic use: cautious prescription is needed! authors.elsevier.com/a/1i1Sw3tB5QxW…

Our study Nature Communications showed a progressive reduction in risk of clinical outcomes following COVID-19 infection and the effect of COVID-19 vaccination in reducing the risk and its persistence. nature.com/articles/s4146… #LongCovid #COVID19 Prof Ian Wong Eric YF Wan Irene Zhang

Our recent study using CDM on Cambridge Core finds immediate declines in mental health diagnoses following population-wide COVID-19 restrictions in France, Germany, Italy, UK, and US. doi.org/10.1017/S20457… #COVID19 #mentalillness Prof Ian Wong Kenneth Man Wallis Lau @HaoLuo429

P-CARDIAC secondary model's paper is finally out! A 10-year CVD risk prediction model for Chinese with established CVD risk. Go check out the article available on European Society of Cardiology European Society of Cardiology Journals #EHJDigitalHealth #P_CARDIAC HKU Medicine HKU Nursing HKU Pharmacy doi.org/10.1093/ehjdh/…

Our study involving 3.6m mother-child pairs in Nature Medicine suggests no direct causal relationship between gestational diabetes and ADHD. Instead, it highlights the importance of considering a holistic risk profile like shared genetic/familial factors. nature.com/articles/s4159…

Our work ⁦BMC Medicine⁩ found 21% of depression incidence increasing during the pandemic but 11-16% less health service used compared with pre-pandemics. The system is recovering with service rebound over 3 years.⁦HKU Pharmacy⁩ ⁦Prof Ian Wong⁩ link.springer.com/article/10.118…

Our amazing work on a seemingly simple but important evidence in Annals of Int Med that statins work well even in old people aged ≥ 85 yrs. Thanks awesome students Wanchun (Wendy) Xu, Amanda, supervisor Cindy Lam and Harvard T.H. Chan School of Public Health collaborator Goodarz Danaei. doi.org/10.7326/M24-00…

Extending early intervention services (EASY Plus) for patients with first-episode schizophrenia aged 15-64 in Hong Kong was associated with reduced self-harm and suicide rates over 20 years, this study finds. ja.ma/3WFXWiY

Study by Yi Chai found that early intervention services #EIS was associated with reduced #selfharm and #suicide rates among all patients with first-episode #schizophrenia #FES. Full study: doi.org/10.1001/jamane… HKU Pharmacy #CSMPR #HKU #HKUMed #HKUPharm #pharmacy #research

Our study reveals persistently elevated rates of psychotropic drug prescriptions beyond the initial phase of the pandemic among patients with depression and anxiety in the post-pandemic era. The Lancet Psychiatry thelancet.com/journals/lanps…

Assessment of COVID-19 with complications post acute phase. Read the full study from Eric YF Wan Irene Zhang Sukriti Mathur Vincent Yan Francisco TT Lai Celine Chui HKU Shirley Xue Li Carlos KH Wong Esther Chan @ CSMPR HKU Prof Ian Wong and colleagues here: bmcmedicine.biomedcentral.com/articles/10.11…

Study in BMC Medicine showed the significant increased risk of multiple disease outcomes with increasing severity in both acute and post-acute phases of #Covid_19 infection, especially among elderly population. doi.org/10.1186/s12916…

Our study using self-controlled case series study showed no increased risk of neuropsychiatric events after fluoroquinolones exposure, with amoxiclav as the active comparator. HKU Nursing HKU Medicine HKU Public Health Laboratory of Data Discovery for Health London School of Hygiene & Tropical Medicine CSMPR_HKU doi.org/10.1002/pds.70…

Our study in BMC Medicine showed a significant increase in the risk of multiple disease outcomes associated with the severity of COVID-19 infection, both during the acute and post-acute phases. bmcmedicine.biomedcentral.com/articles/10.11…

Happy to share the 1st 1st-author PhD publication by my 1st RPg student Yuqi Hu! Published in PLOS Medicine, findings demonstrate an elevated but rather rare risk of hematological malignancy associated with clozapine use #Cancer #schizophrenia dx.plos.org/10.1371/journa…