Thrilled to be a part of this incredible work from the Guttman Lab.

This explainer vid we did describes really cool work at Thomson Lab Caltech. Inspired by our own brain development, researchers demonstrate an artificial neural net that starts with one node, grows, and self-organizes.

From October cover Hot topic #Review by Prashant Bhat, Drew Honson & Mitchell Guttman Caltech describing how nuclear compartmentalization controls gene expression #BiomolecularCondensates #GeneRegulation go.nature.com/3CBHgyj FREE pdf: rdcu.be/ctNBu

Check out our latest work of integrated spatial genomics with seqFISH in the mouse brain cortex, now out in Science Magazine! Congratulations to all authors! science.org/doi/full/10.11…

Why are lncRNAs lowly expressed? How can they regulate their more abundant targets? In our new preprint we explore how these features are balanced to ensure target specificity and robust gene regulation via a spatial amplification mechanism (biorxiv.org/content/10.110…)

Researchers from biologist @MitchGuttman's lab developed a powerful tool that can peer into the world of the cell's genetic material to answer questions about what drives organization of RNA, DNA, and proteins in the nucleus. caltech.edu/about/news/the…

Excited to see our paper featured on the cover of the current issue of Cell (Cell)! On the cover, RNAs scaffold, recruit, and place different building blocks of the nucleus. Artwork by Inna-Marie Strazhnik (Inna-Marie)

Thanks Cell for highlighting our work on the cover of this latest issue! Artwork by the amazing Inna-Marie Inna-Marie depicting RNAs scaffolding, recruiting, and placing different building blocks (e.g., nuclear bodies) inside the nucleus 🎨👩‍🎨👏

Here’s a look inside this week’s Cell - graphical abstract I illustrated to describe work at Guttman Lab Mitch Guttman

This illustration by Inna-Marie, inspired by Waddington’s second most famous drawing, shows with remarkable directness how MultiFate’s 3 transcription factors, interacting in combinations, produce a multistable epigenetic landscape.

Excellent thread by an excellent illustrator. Lots of things everyone should keep in mind when making visuals.

Really enjoyed creating an illustration of Karl Von Frisch to the excellent 4th installment of this series. Astounding 3D animation of insect anatomy and you can finally find out what the world looks like to a bee!

This series is drop-dead gorgeous sci-viz! Entirely a labor of love - Eric applies 3D wizardry to illuminate some pretty dense concepts in bug anatomy/physiology. Glad there’s room for my paintings in there too. #sciart #scientificillustration #entomology #scicomm Guild of Natural Science Illustrators

Why are lncRNAs lowly expressed? How can they regulate their more abundant targets? Our paper published in NatureStructMolBiol we explore how these features are balanced to ensure target specificity and robust gene regulation via a spatial amplification mechanism. nature.com/articles/s4159…

#ICYMI Joanna W Jachowicz &al Mitch Guttman lab show that Xist drives non-stoichiometric recruitment of SHARP/SPEN to inactive X, including @ regions not occupied by Xist via concentration-dependent homotypic assemblies of SHARP required for chromosome-wide silencing nature.com/articles/s4159…

The whole Cai Lab team had a much needed break beneath the trees at Tournament Park. Our resident amateur chef-scientists cooked up an impressive and massive BBQ feast – thank you to everyone who worked so hard to make it a success!

Congratulations to Cai Lab, Hoffmann Lab, David Van Valen, Kai Zinn, and Matt Thomson! These five researchers have been awarded grants from the High-Risk, High-Reward Research (HRHR) Program of the National Institutes of Health (NIH). 👏 caltech.edu/about/news/fiv…