The brain is full of mitochondria! But how many, and where? Different types of mitochondria specialize for energy transformation and other functions In MitoBrainMap v1.0 we provide the first maps of mitochondrial content and OxPhos capacity across the human brain

Our latest study identifies a specific cell type and receptor essential for psilocybin’s long-lasting neural and behavioral effects 🍄🔬🧠🐁 Led by Ling-Xiao Shao and Clara Liao Funded by NIH National Institute of Mental Health (NIMH) 📄Read in nature - nature.com/articles/s4158… 1/12

Our April issue is now live! nature.com/neuro/volumes/…

Molecular dynamics study of differential effects of serotonin-2A-receptor (5-HT2AR) modulators biorxiv.org/content/10.110…

Withania Somnifera (Ashwagandha) has been used for centuries in Indian traditional medicine as an 'adaptogen' that boosts stress resilience, but the cellular mechanisms and key beneficial bioactives that drive putative neuroprotective effects remain unclear Sashaina Fanibunda

What an important study this is for India - "The demographic history of India is also unique, with exposure to different environments and widespread admixture, followed by formation of numerous endogamous groups". nature.com/articles/s4158…

The brain consumes a disproportionate amount of energy relative to its size

Assessing the potential cardiovascular risk of microdosing the psychedelic LSD in mice biorxiv.org/content/10.110…

Happy to have a brand new Dr. minted from LT lab! Congratulations Dr. Deepanshi Gahlot!! She is a thinker in the lab and I really enjoyed witnessing her research journey on engineered LC3 protein in autophagy (work coming out soon!!)

Successfully defended my Ph.D. yesterday! Grateful for the guidance of my advisor, Lipi Thukral, and the constant support from my lab mates, collaborators, friends, and family. Excited for what lies ahead, but for now… just letting this moment sink in.

Over 20 years ago, Zuker et al. discovered the mammalian sweet taste receptors Now, an exciting collaboration between our labs Biochemistry & Molecular Biophysics reveals the #cryoEM structure of the human sweet receptor-key to sweet taste perception-online Cell! sciencedirect.com/science/articl…

Wow, wow, wow!!! The structure of human sweetness cell.com/cell/fulltext/…

Thalamic activity is required for the execution of learned movements. nature.com/articles/s4158…

Striatum supports fast learning but not memory recall nature.com/articles/s4158…

Please see this new publication by Arthur Godino, Marine Salery, and others now online in nature. We show opposite roles for D1 vs D2 dopamine receptor- expressing neurons in ventral hippocampus in controlling approach-avoidance behavior. Friedman Brain Institute rdcu.be/ek2DS

Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & for myself, expanding my inpatient neuropsychiatry work to the service

BREAKING: MIT just completed the first brain scan study of ChatGPT users & the results are terrifying. Turns out, AI isn't making us more productive. It's making us cognitively bankrupt. Here's what 4 months of data revealed: (hint: we've been measuring productivity all wrong)

My postdoc work "Unsupervised pretraining in biological neural networks" is out now, along with more than 400GB (milliions neurons) neural data. nature.com/articles/s4158…. Figshare and Github links can be found in the paper.

Inauguration of ARUMDA National Analytical Facility for Nutrition & Metabolism Research by Dr. A.K. Mohanty (DAE-Secretary). Dignitaries: Dr. Anil Kakodkar (former DAE-Secretary), Prof. Chengalur (Director-TIFR), Prof. M. Krishnamurthy (Center-Director-TIFRH).

Cortical closed-loop electrical stimulation can prevent pathological hippocampal-cortical communication and preserve long-term memory in focal epilepsy Dion Khodagholy Ahnaf Rashik Hassan UCI Engineering Neuroelectronics & Cognition UC Irvine UCI Epilepsy Research Center nature.com/articles/s4159…