Check out this super cool work from Felix Horns 👇👇

Check this out! Our latest effort to reconstitute a multicellular circuit from bottom-up. Never bored of staring at those stunning fluorescence time-lapse movies.

My "Friends don't like friends make bad graphs" repository reached 800 stars! Thanks everyone. github.com/cxli233/Friend…

Thrilled to receive Science & SciLifeLab Prize in my category! Thanks again for the amazing support during my PhD Cai Lab Caltech. I am also super excited for the future of the spatial multi-omics field! science.org/doi/full/10.11…

We're hiring another lab technician! Are you a recent college grad looking for research experience before grad/med school? Are you interested in gene therapy to preserve vision? Please reach out by email/DM! Find out more about our lab at: amamotolab.com

Just posted a preprint on our new spatial genomic recording system, baseMEMOIR. biorxiv.org/content/10.110… Motivation: Cells divide, differentiate, and migrate to form exquisitely organized tissues. Reconstructing the dynamic histories of individual cells, including their lineage

Our paper on lineage motifs is now online at Developmental Cell 😀 We hope that this approach will be widely useful for anyone interested in analyzing tree-type datasets!

Delivering and expressing a gene in cells is usually a messy (heterogeneous) process. The messiness interferes with research and applications such as gene therapy. In two new papers, we introduce a toolbox of synthetic miRNA-based control circuits that enable more precise, gene

Pleased to share that this project from my PhD is now published in NatureEcoEvo! Many thanks to my amazing supervisors Prof Francois Balloux and Lucy van Dorp - I could not have done it without them. Link to paper -> nature.com/articles/s4155… (1)

Excited to have lineage motifs out in the world. Hoping the concept and methods can be useful in various developmental systems as more lineage data become available. Congratulations to Martin Tran and Amjad Askary on the work, and thanks to Adara Koivula and Inna-Marie for

Check out this useful tool for discovering patterns in your spatial datasets from Amjad Askary 🤩

A long sought after hypothesis has been that organizing biomolecules in and around nuclear bodies is essential for functional RNA processing. We now provide direct evidence of this in nature for nuclear speckles and mRNA splicing. Check out this thread! nature.com/articles/s4158…

Excited to share our new work!!🥳How do cells lose totipotency to fate segregation? w Zernicka-Goetz Lab we found that early blastomeres experience a "Composite State" by displaying dual-lineages signatures! Link for full text👉: rdcu.be/dITfo

The evolution of developmental biology through conceptual and technological revolutions: Cell cell.com/cell/fulltext/…

Check out this awesome work from Will — a huge step towards the dream of multiplexed long-term recording of cellular histories.

The lives of cells, recorded go.nature.com/4g2gRwG #Perspective by Amjad Askary, Wei Chen, Junhong Choi, Lucia Y. Du, ElowitzLab, @james_gagnon, Alex Schier, Sophie Seidel, Jay Shendure, Tanja Stadler & Martin Tran

Synthetic biology could enable new types of programmable therapeutics. Our new preprint introduces synthetic protein circuits that selectively trigger cell death in Ras-mutant cancer cells, with interesting advantages compared to existing approaches. biorxiv.org/content/10.110…

I'm excited to share our new preprint on LagTag, a method that recovers both past and present chromatin states from the same mammalian cells. biorxiv.org/content/10.110…