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Wonderful to have this work led by Travis Fleming along with other colleagues in our laboratory, as well as great collaborators, out on bioRxiv! Stay tuned for exciting complementary work from Dorien Pastoors, Ruud Delwel, and co coming soon!

Excited to share our preprint (@D_Pastoors): "MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia"! biorxiv.org/content/10.110… MECOM is a TF whose overexpression leads to aggressive AML and with an immature phenotype. [1/15]

I am grateful to be a part of this amazing group. Thank you to ASH for supporting my research and career development! And to my mentor@bloodgenes and Dana-Farber/Boston Children's for training me🙏

Excited to share my analysis of the Cancer Dependency Map! My goal was to systematically identify biomarker - dependency relationships in order to identify new anti-cancer targets and understand how to stratify patients to make those targets clinically useful.

I am grateful to Damon Runyon Cancer Research Foundation St. Jude for supporting my work and to Vijay Sankaran for the mentorship🙏 Very excited to meet my peers / this year’s class at the upcoming meeting! damonrunyon.org/news/entries/8…

Alessandro Donada sat down with Dorien Pastoors and Travis Fleming for a deep dive on their latest AML biology preprints. Watch the #SimplyBlood 🩸 interview today simplyblood.org

Very excited to share that my thesis work is out in Molecular Cell! We trained a Structure and Omics informed Classifier (SPOC) to score binary AlphaFold multimer (AF-M) predictions by structural quality and consistency with experimental omics datasets. cell.com/molecular-cell…

In our tests, SPOC outperforms other commonly used metrics in prioritizing biologically relevant interactions in large scale AF-M screens. We used SPOC to score ~40,000 binary pairs across ~300 genome maintenance proteins. View all data and use SPOC on: predictomes.org

A season to remember, and it's just our beginning. 🔱 #GoTritons

Predictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactions dlvr.it/TJgZXl

super fun game from the inimitable Ernst Schmid - check it out!

We at voitlab.org are grateful to Children’s Cancer Fund for supporting our work. Thank you also to Dallas Cowboys Dak Prescott, Jalen Tolbert, Tony Romo, Troy Aikman for using their platform to raise awareness and funds for pediatric cancer research. youtu.be/KZwX8Mf7n5I

Joining the Voit Lab is the best decision you will ever make. Go work with Richard if you can!