Please check out our review article on Tumor Innervation in Journal of Clinical Investigation. Stefan Gysler does a great job of describing how nerves contribute to tumor growth. Exciting biology in the TME! Professor De Silva Anirban Maitra BasserBRCA Ovarian Cancer Research Alliance Tina's Wish jci.org/articles/view/…

Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response | Nature Cancer nature.com/articles/s4301…

After the second Pfizer dose I can now empathise with my cells needing a recovery day after transfection.

Please check out our (Roger Greenberg) review article on the "Communication between chromatin and homologous recombination.” We discuss recent seminal findings on how alterations in chromatin impact BRCA-mediated repair.authors.elsevier.com/c/1dBSR,LqAZQ9…

Looking forward to sharing our research along with Igor Brodsky at the InflammaZoom seminar next Monday at 1pm BST (8AM EDT). Many thanks to Clare Bryant ([email protected]) & the other organizers for the kind invitation!

NEW content online! Targeting the DNA damage response in immuno-oncology: developments and opportunities dlvr.it/S5NMp2

Congrats to the PCGI labs of Dr. Junwei Shi Shi Lab @ UPenn and R. Babak Faryabi R. Babak Faryabi, in collaboration with colleagues in the Berger Berger Lab and Bernt labs, for their article on ZMYND8 regulation of the IRF8 transcription axis.

Our lab is hiring! Please check out this great opportunity for a recent graduate to learn cutting-edge molecular biology and contribute to awesome science in a friendly lab environment! linkedin.com/jobs/view/2671…

Check out new research from PCGI Leaders Drs. Michael Lampson and Mia Levine:

AlphaFold models of the 144 largest human proteins.

Thanks, Vanessa. Inviting everyone to join what promises to be an excellent symposium! Join us The Francis Crick Institute for this hybrid event.

NOTE Time Change to 11 AM for Tomorrow's Colloquium Seminar - mailchi.mp/upenn/tuesday-…

"We identify a phenotypically distinct tumor microenvironment in the BRCA1/2mut tumors with evidence of increased immunosurveillance." Looking forward to reading this paper! Congrats Anniina Färkkilä! BasserBRCA Penn Ovarian Cancer Research Center @CanaryFound

#NIH is seeking input on challenges affecting retention in the postdoctoral trainee community. Better understanding of these challenges will help NIH support competitiveness & innovation within biomedical research & its workforce. RFI deadline is 4/14: bit.ly/3E8fRGz

… I heard there are some great talks here at IOTN Moonshot See me later on CNN 😂

How do unique patterns of chromothripsis emerge in cancer and genomic disorders? Now out nature, we show that CIP2A-TOPBP1 tethers pulverized chromosomes from micronuclei, drives its asymmetric inheritance, and promotes a distinct rearrangement signature. nature.com/articles/s4158…

Excited to share our recent work on KaryoCreate, a new method to engineer chromosome-specific gains and losses in human cells with Stefano Santaguida and Giunta Lab cell.com/cell/pdf/S0092… Check out also recent similar and complementary work by Susanne Lens and @McClellandLab!

We made it to the newsletter! #Germany #Mexico Penn Postdoctoral Association

Check out our latest paper, published Nature Communications. We show that STING activation induces IL18 secretion and thereby enhances CAR T function. Great collaboration between @CarlHJune lab and James Chen UT Southwestern Medical Center. Penn Medicine Penn Medicine MD Penn Postdoctoral Association nature.com/articles/s4146…