Stuart's songs of the year 2023 open.spotify.com/playlist/5mQCz…

beautiful and heartwarming story for the end of the year ❤️

A UNIX family tree someone posted to fb. Original source unknown to me. #unix

ICYM our brilliant 2023: A stunning year of medical breakthroughs for Queenslanders @QIMRBerghofer couriermail.com.au/news/queenslan… via The Courier-Mail Jackie Sinnerton

If you're aged 50-65 years and have a family history of glaucoma (affected parent and/or sibling) but no personal history of the disease, we invite you to be part of our study. Apply here: qimrberghofer.edu.au/genetics-of-gl…

This means Australians are being left behind. Our future prosperity, health, environment, and security depends on it. Australia being ‘left behind’ as federal research and development funding sinks to 30-year low theguardian.com/business/2024/…

We will add an asterisk symbol next to our names with the caption 'These authors contributed equally to this work'

Very sadly, we have learned of the death of Professor Peter Armitage, CBE. Peter, who worked in a forerunner of the Unit 1947-1961, was a pioneer in developing statistical methodology for medical research. Our annual Armitage Lecture began in 2003 to honour this special man.

Mendelian Randomisation (MR) is going to hell in a handcart, with an exponential weekly increase of papers with Mendelian Randomisation in the title, most of them nonsense. 25th April 4.30pm online or in person UCL I'll talk about what should be done forms.office.com/pages/response…

Congratulations to Professor Stuart MacGregor on being awarded a highly competitive national funding grants for crucial research into #glaucoma risk prediction. The NHMRC’s Investigator Grants were announced on Thursday...

After 20 years and 42 days, Illumina's patent covering DNA microarray normalization, clustering, and genotyping, together known as Illumina GenCall, filed on March 24th 2004, has expired patentcenter.uspto.gov/applications/1… 1/8

Sobering reading for any one who has put countless hours into grant writing (or been on a review panel)

Today we opened a web portal for our 210,000 biobank participants! We currently return results on: - Genetic & cumulative risk for cardiovascular disease and type 2 diabetes; - Pharmacogenetics reports; - Ancestry information; - Fun facts, e.g.caffeine metabolism & % Neanderthal.

Cigarette sales and lung cancer deaths are the same curve, shifted 25 years.

Two impressive nature papers on the genomics of colon cancer, linking with outcomes, identify new mutations, likely role of diet and strengthen the case for sequencing to be used in medical practice nature.com/articles/s4158… nature.com/articles/s4158…

Kind of a big deal: GPT-4 simulates people well enough to replicate social science experiments with high accuracy Note this is done by having the AI prompted to respond to survey questions as a person given random demographic characteristics & surveying thousands of "AI people"

A 5-year observational study of ~12,000 individuals with obesity taking GLP-1 drugs (without diabetes) with propensity matched controls A significant reduction of all-cause mortality (HR 0.23, 95% CI 0.15, 0.34) …ubs.pericles-prod.literatumonline.com/doi/10.1111/do…

probably Theseus, but it’s changed over time

#AAHMSFellow Stuart MacGregor of QIMR Berghofer is a world authority on the conduct and analysis of genetic association studies. He has led studies which have mapped hundreds of genes for diseases ranging from skin cancer to eye disease.