Excited to announce that the 661K resource is now live at Plos Biology PLOS Biology journals.plos.org/plosbiology/ar… We uniformly assembled, ran quality control and performed general characterisation on 661,405 bacterial genomes that were in the ENA at the end of November 2018.

The plasmid gene aac(6’)-Ib-cr confers 4x increase in MIC to cipro in strains already harbour resistant gyrA and parC mutations. This dual resistance combination shows strong association with emerging carbapenem resistant clones. journals.asm.org/doi/10.1128/AA…

Many thanks to everyone involved for the hard work and to the anonymous reviewers for the very constructive comments! journals.plos.org/plospathogens/…

Please RT: We are looking for a postdoc or research associate/technician to join a multidisciplinary team on an antibiotic discovery project combining high-throughput microscopy, imaging AI, and chemical AI. See bit.ly/3F854La. Apply at [email protected].

Merry Christmas from the Bakery! bit.ly/3yIGHkB Our first combined wet and dry lab work - why has one AMR plasmid globally disseminated among Shigella and another has not? Led by @MalakaDes with @Jaws_Stenhouse Grace Blackwell Rebecca Bengtsson Claire Jenkins @JPJHall

RpoN/Sfa2-dependent activation of the P. aeruginosa H2-T6SS and its cognate arsenal of antibacterial toxins. Luke Allsopp Tom Wood Filloux lab academic.oup.com/nar/advance-ar…

What factors are required for bacterial fighting? Our latest study in @NAR_Open shows that the H2-T6SS and its effectors requires the regulators Sfa2 and RpoN in #Pseudomonas Great work Alice Collins Eleanor Tom Wood Filloux lab @CMBI_Imperial NHLI academic.oup.com/nar/advance-ar…

We search a #PhD student to join the team. Exciting, interdisciplinay project investigating new host defence mechanism and their subversion by #bacteria (#Legionella) Wellcome-Wolfson Institute Experimental Medicine. #microbiology #cellbiology #biochemistry findaphd.com/?pj=139820 DM me for info. RT please!

Political interference in the selection of research grants is eroding Australia’s international reputation and the integrity of Australia’s research system. Of the 4 known occurrences of political interference, 3 have occurred in the last three years. science.org.au/news-and-event…

Still time to apply for a PhD project in my lab to investigate the interface between K. pneumoniae T6SS and macrophages. Fun project in an international and supportive environment.findaphd.com/phds/project/d…

Our research shows that efficacy of tetracycline class antibiotics can be restored to treat MDR Acinetobacter baumannii infection. Great collaborative effort Brian Forde Schembri Lab David Paterson Mark Blaskovich Christopher McDevitt Mark von Itzstein AO journals.asm.org/doi/10.1128/mb…

Clémence Whiteway, Adam Valcek, PhD and @AnkeBreine from the Van der Henst Lab lab gave themselves a X-mas present:)👉nature.com/articles/s4139… describing a new mechanism for capsule formation and virulence in the bacterial pathogen Acinetobacter baumannii. VIB VUB

We are looking for a postdoc or research associate/technician to join a multidisciplinary team on an antibiotic discovery project combining high-throughput microscopy, imaging AI, and chemical AI. See bit.ly/3F854La. Apply at [email protected].

Diversity and distribution of type VI secretion system in bacterial plasmids. assets.researchsquare.com/files/rs-13214…

Abstract submission is open for the 2022 Focused Meeting, Protein Secretion at the Host–Pathogen Interface, taking place 3–4 November in Belfast. Submit your abstract before 15 July. microb.io/3uF3YT3 #HostPathSecretion22

PRETTY COOL STUFF on WaaL, the O-antigen ligase for building LPS. These folks were amazing to work with! Filippo Mancia Khuram Ashraf Rie Nygaard David I Roper Chris LB Graham Oli B. Clarke Meagan Belcher Dufrisne Vasileios Petrou & others nature.com/articles/s4158…

Cool paper on UPEC glycan-adhesin interactions in the gut. journals.plos.org/plospathogens/…

"Climbing has a weight problem." Read more in the article below 👇 climbing.com/news/ifsc-medi…

We discussed shipping strains today and it was surprising to me how much of it is still done in LB agar stabs. That is risky if genomic integrity matters - see paper below and this short thread 🦠📬👇🏼. 1/4 bmcmicrobiol.biomedcentral.com/articles/10.11…

Very excited to share our work on NMEC led by Nhu Nguyen (under review by eLife). We highlight that even with appropriate antibiotic treatment, causative NMEC that resides intestinally might not be eliminated and can cause relapse. medrxiv.org/cgi/content/sh…