Congratulations on this super interesting story! Very excited to see that ERH protein not only assembles heterochromatin in S. pombe but also in mammals. Amazing conservation!!

The Laboratory of Biochemistry and Molecular Biology, NCI ccr.cancer.gov/laboratory-of-… is recruiting tenure-track investigators! Candidates working in the general area of Chromosome Biology should apply to the NIH wide Stadtman Investigator search by Sept. 30 irp.nih.gov/careers/trans-…

Nice work showing dimerization of CENP-B forms DNA loops. Wonder if the authors are aware of our work showing that dimerization of CENP-B bound to retrotransposon LTRs promote clustering, resulting in loop formation. Fig 5, 6 and model 6e in nature.com/articles/natur… Molecular Cell

I’m excited to be recruiting for the lab’s first #postdoc to help us at MSU Biochemistry & Molecular Biology investigate epigenetic state determination and rewiring. Please RT and have applications go through the posting below! Thanks! careers.msu.edu/cw/en-us/job/5…

PRIMING EPIGENETIC INHERITANCE!! Ever wonder what determines heritability of a silenced chromatin domain? Histone deacetylation, a conserved heterochromatin feature, is the key to preserving modified histones (H3K9me3) that transmit epigenetic memory nature.com/articles/s4159…

Prime, Protect and Preserve epigenome: HDACs can do it all! Congratulations Martin Shiv Grewal !! Thrilled to be a part of this beautiful work👇🏻

So sad to learn about the untimely demise of a dear friend and colleague David Allis, a giant in the field of chromatin/epigenetic research. He will be sorely missed! Condolences to his family

Online Now: The molecular basis of heterochromatin assembly and epigenetic inheritance dlvr.it/SpDz1L

UNRAVELLING THE MYSTERIES OF HETEROCHROMATIN! Ever wonder how silenced heterochromatin domains are stably propagated? This article describes the conserved principles by which modified histones and HP1 condensates promote self-propagation of heterochromatin authors.elsevier.com/a/1h5x43vVUPNx…

Thank you Nitika Taneja!

Beautiful work, congratulations Shiv Grewal, Diego Folco, Hua Xiao, and team.

📢An elegant dance between replication and histone retention for epigenetic inheritance!🥳Our new work shows that heterochromatin domains are specialized replication zones that preserve parental modified histones to ensure self-templated chromatin assembly bit.ly/4b8wpNA

Replication Factors Preserving Epigenetic Marks Within Heterochromatin Domain Promote Epigenetic Inheritance. Nicely work. Huge Congratulations to Shiv Grewal, Patroula Nathanailidou and coauthors.

Online Now: Nucleosome remodeler exclusion by histone deacetylation enforces heterochromatic silencing and epigenetic inheritance dlvr.it/TBPsB9

📢ACCESS DENIED!! Ever wonder how heterochromatin causes transcriptional gene silencing and is epigenetically inherited? Excited to share our new story showing that histone deacetylation, a conserved feature of heterochromatin domains from yeast to mammals, limits access to

Happy to share our work about DNA supercoiling, an understudied physical feature of the double helix and the chromatin. 1/5 nature.com/articles/s4159…

Hurry! The deadline to register for the exciting symposium on "Histone Modifications and Chromosome Structures" is quickly approaching—this Friday, October 4, 2024. This symposium featuring talks by 25 renowned scientists is free to attend. To secure your spot, please visit:

📢New Publication Alert📷 The PhpC/NF-Y, a pioneer like TF complex, accesses heterochromatin to drive the transcription of a cryptic intron-containing transcript to initiate silencing. A big thank you to Shiv Grewal and all the amazing coauthors for their invaluable contributions!

#authorinterview Dr. Manjit Kumar Srivastav Manjit Kumar Srivastav working with Dr. Shiv I.S. Grewal lab Shiv Grewal NIH talks about his work on "Pioneer transcription factor infiltration triggers de novo heterochromatin assembly" Molecular Cell . biopatrika.com/academia/resea…

Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development dlvr.it/TMNgYR