New Implant Offers Hope for Easing Rheumatoid Arthritis --> pretty cool way to treat RA via vegus nerve. "The SetPoint System is an inch-long device that is surgically implanted into the neck, where it sits in a pod wrapped around the vagus nerve, which some scientists believe

This alone justifies the trip to Kyoto.

Longevity companies are exploring investments in Montana in a bid to make it a medical tourism hub wsj.com/tech/biotech/t… via The Wall Street Journal

Honestly, this article is too long and meanders. But the key point stands: we need to stop micro-plastic pollution because it will do more to damage health and stand in the way of our longevity than any other cause. "Plastic has been found in human hearts and kidneys and other

The new hard tech era is here alright! This article didn't interview us (why not? ☺️) - but it did show our co-work space at Shack15 and described our thesis! Civilization VC ranked Top 3 in AI x Bio. Let's go! Silicon Valley Is in Its ‘Hard Tech’ Era nytimes.com/2025/08/04/tec…

Conflict is not the enemy. Conflicts - of ideas, strategies, and even personalities - are the only true path to growth. Thesis + antithesis --> synthesis. So the real enemy is the lack of humility that will prevent you from learning from inevitable conflicts, or admitting when

Shahram Seyedin-Noor Love it Shahram. You're right it's the path to growth. Bezos and Amazon are well known for this. Instead of agreement choosing conflict coz it leads to best ideas. Also disagree and commit—bash ideas and once decision is made everyone getting behind them

"Yankner and his team linked lithium loss with other markers of the disease, including a build-up of tau protein tangles and altered activity of Alzheimer-related genes. They even identified a potential means to break the deleterious cycle." New hope for Alzheimer’s: lithium

AI is the fourth member of our investment committee Civilization VC. That's not an exaggeration.

most likely due to the lentiviral vector. “As of July 2025, hematologic malignancies have been diagnosed in 10 (15%) of 67 clinical trial participants, compared with three (4%) incidents at the time of Skysona’s initial approval, according to the FDA.” share.google/6kNYnMktxeCzcK…

The famous rock tumblr metaphor you need to hear as a founder.

I wrote about how genetic risk works in the context of embryo selection and how people often think about it all wrong. A short 🧵:

X vibe poll: 🗳️ are you more optimistic or pessimistic about the next 3 years?

What's more interesting than 100,000,000 data points? 1 BiLLION singe-cell datapoints! Virtual Cell x AI x Bio = new medicines Civilization VC is happy to back our friends at Tahoe Therapeutics Nima Alidoust Hani Goodarzi Kevan Shokat Johnny Yu

I think it is worth talking about the 1 Billion cell milestone. This is not because 1Bn is a large and round number (or at least not entirely)! These number of cells, with the rich perturbative type of data that Tahoe Therapeutics's platform generates, puts the number of training tokens

“When I entered Gaza the Israeli military had a rule: I was only allowed to bring in three kilos of food. As I was weighing out protein bars, trying to get under the limit, I said to my husband: ‘How sinister is this?’ I’m a humanitarian aid worker. Why would there even be a

The optimists have it!

One of the most powerful strategies for long-term success is to not follow the herd, to be contrarian. Just look at Palantir when it started, or SpaceX or Tesla. Far-fetched ideas that only seem obvious in hindsight. The most successful companies that we’ve invested in

You don’t need to own a huge chunk of your company to become a big success. You just need enough. #Bezos points to 10 to 20%. He gave up 20% of his company for the first million he raised from 22 angels! The average YC company now raises at 4x that valuation, and how many

ChatGPT just hallucinated that I worked at Flagship. Not sure if that's good or bad. 😂