Super excited to say that our new paper is out on medRxiv! We apply and discuss the use of Mendelian randomization to estimate the causal role of the gut microbiome in colorectal cancer. #Mendelianrandomization #colorectal #cancer medrxiv.org/content/10.110…

How many of you know what Cruella Braverman's Public Order Bill contains? It's frankly unbelievable: legislation you might expect in Russia, Iran or Egypt. Here's a summary from my column today:

New pre-print available: "Violation of the constant genetic effect assumption can result in biased estimates for non-linear Mendelian randomization" available at medrxiv.org/content/10.110…. An update that no scientist ever wants to give. Thread follows:

Our data note describing the inflammation proteomics dataset measured by Olink Proteomics in 9000 Children of the 90s participants is now out in WellcomeOpenResearch doi.org/10.12688/wellc… 1/3

Delighted to see our work on the metabolic features of genetic liability to type 2 diabetes and coronary artery disease published in eBioMedicine – The Lancet Discovery Science today! Joshua Bell @emmylooroll Caroline Bull Eleanor Sanderson george davey smith Michael V Holmes (he/him) thelancet.com/journals/ebiom…

We have a new short preprint up examining two commonly used non-linear Mendelian randomisation approaches using negative controls in the wake of recent concerns about their performance medrxiv.org/content/10.110…

Do you consider doing a PhD in statistical human genetics in a wonderful location? My lab [wp.unil.ch/sgg/] has open position(s) to explore human interactions, region-specific effects, evolutionary optimal transcript levels by developing advanced causal inference methods

Big new article from me in PLOS Biology on the past, present and future of science publishing. 6n 🧵 on what I try to do here. (RTs appreciated). 1/n doi.org/10.1371/journa…

Overpublishing puts enormous stress on students and PIs. And brings tons of money to publishers in STEM. A new study shows that the number of papers is increasing FASTER than the number of #PhD graduates. It’s an amazing work with very useful statistics. Huge kudos to the

Really pleased to see our paper published in eBioMedicine – The Lancet Discovery Science this week. We found that weight loss in people recently diagnosed with type 2 diabetes altered levels of cancer-related proteins in blood🩸. …w-sciencedirect-com.bris.idm.oclc.org/science/articl…

We are seeking a mol/genetic epidemiologist or bioinformatician to work at MRC IEU in Bristol, UK. Please get in touch if you are interested! #datascience #Bioinformatics bris.ac.uk/jobs/find/deta…

1/4 Excited to share our latest preprint where we used observational and Mendelian randomization methods to explore the role of metabolites as intermediates between adiposity and endometrial cancer using data from UK Biobank (UK Biobank). medrxiv.org/content/10.110…

We have an exciting 3-yr postdoc position at Imperial College London using molecular #epidemiology to understand adiposity-driven pancreatic #cancer. Possibility of hybrid working. Deadline 24/07 Mattias Johansson Richard Martin @Karl_SmithByrne Emma Vincent Pls retweet🙏 twtr.to/4oSz9

If you have access to myeloma samples/data get in touch - we’d like to expand these analyses! #EpiTwitter

We are re-advertising for an exciting 3-yr postdoc post at Imperial College London using molecular #epidemiology to understand adiposity-driven pancreatic #cancer. Competitive salary and hybrid working options. Deadline 4/11. Email if interested! Pls retweet🙏shorturl.at/vm8BB

Interested in combining genetic epidemiology with other methods to identify modifiable causes of disease? If so a research fellow post with MRC IEU with gibran hemani and me now available bristol.ac.uk/jobs/find/deta…

✨#PhD opportunity with myself, Jane Masoli and Jack Bowden We will use #genetics to study how #cardiovascular risk factors vary with age, to improve mechanistic understand and clinical risk prediction🧬📈 Funded for 3.5 years! Deadline 3rd December University of Exeter #ASHG24

Really enjoying this double conference IGES and ASHG trip so far! Come to poster 8006 at 2.30 to hear about how where we carry fat tissue influences our risk of cancer! #ASHG2024

Come join us (virtually) next month for Gen Epi training!