Roybal Lab
@roybal_lab
Updates from the Roybal Lab at UCSF. We are focused on engineering the next generation of immune cell therapeutics.
ID: 1369701914347147264
http://www.roybal-lab.org 10-03-2021 17:31:25
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Today #AACR21: Kole Roybal on-demand session "Towards Engineering of Neoantigen-Specific T-Cell Therapies" followed on 4/13 with panel discussion. Cell Design Institute UC San Francisco UCSF Bakar ImmunoX Initiative Parker Institute for Cancer Immunotherapy | See full list of @UCSF presentations: ow.ly/r78q50Elalq
Two teams have created a new generation of highly specific CAR T cells, which safely cleared solid tumors in mice with mesothelioma, ovarian cancer, and the deadly brain cancer glioblastoma. Read more in Science Translational Medicine: ➡ fcld.ly/pf2d4wc ➡ fcld.ly/tb2q2ir
Congratulations to Roybal Lab members Axel and Julie for their publication in Science Translational Medicine! This paper investigates novel synNotch CAR circuits that enhance tumor recognition through combinatorial antigen signatures in mesothelioma and ovarian cancer.
Excited to share new work w/ co-lead Camillia Azimi, @MarsonLab Jeff Bluestone Roybal Lab: using a method we call 'CAR Pooling', we tested many CARs in multiplex & found new non-T cell signaling domains which improve CAR-T efficacy. biorxiv.org/cgi/content/sh… 👇🧵 1/10
Congratulations to Camillia Azimi for her Graduate Women in Science Fellowship Graduate Women in Science awarded to just seven outstanding women scientists during the 2020-2021 funding cycle. Exceptional work Camillia, you continue to impress! #womeninSTEM #womeninscience
Excited to share our paper Cell tinyurl.com/22s9pztn. Ray Liu and Iowis Zhu led the development of clinically optimized and tunable nextgen synNotch receptors dubbed SNIPRs for cell therapies. Thank you UC San Francisco Gladstone Institutes Parker Institute for Cancer Immunotherapy press: tinyurl.com/2p8usz7z
Why test #celltherapies one-by-one when you can use #SynBio to design, learn, and iterate on thousands in parallel? Our team UC San Francisco @MarsonLab Roybal Lab is #hiring a wetlab technician to help build the next revolution in genetically engineered medicine! DM for info & please RT!
Read our work in Science Translational Medicine - beautiful work by Daniel Bryan Goodman and Camillia Azimi !
