
Rossjohn lab
@rossjohnlab
Led by Prof @Jamie_Rossjohn FRS we are focused on understanding molecular bases underpinning protective and aberrant immunity
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https://rossjohnlab.com 26-07-2014 11:43:04
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latest paper from the lab describing crystal structure of the human LAG-3-HLA-II complex, in collaboration with Immutep Monash University Science Immunology Australian Research Council Prof. Jamie Rossjohn science.org/doi/10.1126/sc…



Latest paper from lab, where Awad et al describe how cigarette smoke impacts that MAIT-MR1 axis and implications for lung diseases. In collaboration with Fairlie, Hansbro and Corbett labs doi.org/10.1084/jem.20… Monash Biomedicine Discovery Institute NHMRC Wael Awad Monash University Prof. Jamie Rossjohn Journal of Experimental Medicine




science.org/doi/10.1126/sc… First paper from the The Johnstone Lab for the year and a brilliant collaboration with Doherty Institute colleagues Dan Utzschneider and Alex Kallies. Thanks to all Peter Mac Research Peter Mac Cancer Centre for help and support and great job Dane Newman and Leonie Cluse!

TCR-peptide-HLA ternary structures define molecular mechanisms of TCR cross-reactivity toward natural influenza variants Science Immunology science.org/doi/10.1126/sc… Rossjohn lab Prof. Jamie Rossjohn Kedzierska Lab Katherine Kedzierska


Our latest study Science Immunology identifies the molecular determinants of cross-reactive B35/NP418-restricted CD8+ T cells across IAVs from 1918 H1N1 to 2024 H5N1, and assesses their functionality. Katherine Kedzierska Rossjohn lab science.org/doi/10.1126/sc…

Researchers in Science #Immunology have identified CD8+ T cells from human donors that can recognize naturally occurring influenza variants spanning more than 100 years, including the 1918 influenza A and 2024 #H5N1. Prof. Jamie Rossjohn Kedzierska Lab scim.ag/4hpSzh1


🚨 Flu breakthrough! 🚨 Researchers at Doherty Institute & Monash University have discovered immune cells that recognise flu viruses even as they mutate—a further step toward a universal flu vaccine. go.unimelb.edu.au/d7z8 UniMelb MDHS The Royal Melbourne Hospital Oanh Nguyen Prof. Jamie Rossjohn Kedzierska Lab


In collaboration with 💮Nicole La Gruta and colleagues, latest paper from Prof. Jamie Rossjohn lab describing role of Lck-coreceptor assocation in T cell function. Monash University science.org/doi/10.1126/sc…

Recent paper from lab describing a peptide-independent MHC-restricted T cell receptor nature.com/articles/s4146… in collaboration with La Gruta lab Monash University Monash Medicine, Nursing and Health Sciences Rossjohn lab Nature Communications

Our latest paper demonstrating the potential of “our” DOT cells against colorectal cancer has just been published in Nature Cancer: rdcu.be/ehYwG Many congrats to the whole team, especially Rafa Blanco Domínguez! :)


Your immune system gradually loses it top team players when we get older 👱➡️👵 Our study in eBioMedicine – The Lancet Discovery Science investigates how long our good immune cells stay around – a 🧵⬇️ go.unimelb.edu.au/4sep Carolien van de Sandt Katherine Kedzierska Doherty Institute #Influenza #AgingResearch


In collaboration with Moody lab, latest paper from Rossjohn lab describing the structure of a lipopeptide bound to a MHC-I like molecule found in chickens - hopefully this study will not ruffle too many feathers.

