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💭CS on ICU are only truly indicated in very specific situations, and very debatable in many others! So not just a rescue for every very sick patient. 💊Risk of infections is related to the (cumulative) dose. Define net immune status of your patient, in its specific environment.

😷The group of immunocompromised patients we are currently treating is evolving in its complexity. 🍄This shift results in more difficult presentations of mold infections, posing significant diagnostic and therapeutic challenges. ⚕️Interesting considerations on bIMI! #IDtwitter

Academic publishing: Scientists submit their work (often done in unpaid time) Reviewers review it - for free Then - the journal then charges people to read it or charges the *authors* ENORMOUS open access fees And the few staff they do pay? They pay poorly What a scam!!

🆕📰 Risk factors and outcome associated with #fungal 🍄 infections in patients with severe #burn injury 🔥 → Our 10 year IFI-BURN from Hôpital Saint-Louis AP-HP study with Emmanuel Dudoignon just out in Clinical Infectious Diseases Stay tuned, more to come… ! In long 👉 doi.org/10.1093/cid/ci… In short👇

🔔ORAL amphotericin B formulation (MAT2203)🔔Compassionate use in 5 cases (Rhodotorula, Candida krusei, Fusarium² and Histoplasma) -> in an area of azole resistance, coinfections and increase of non-Aspergillus mould infections something to keep an eye on. academic.oup.com/ofid/article/d…

Feeling so honored, what a team! Let’s go! 🍄

🇩🇰Azole resistant Aspergillus fumigatus was found in 20% of the 366 environmental samples taken in Denmark (4.2% of all 4,538 isolates were azole resistant). ‼️ Dual use of azoles in clinical medicine and for crop protection challenges patient management! #aspergillosis #fungi

Clinical Microbiology and Infection #RCT proposal to test if 10-day #antifungal treatment for #candidemia is as effective as the 14-day standard. This could improve outcomes 📈, reduce resistance 🛡️, and lower healthcare costs 💰. Stay tuned! 👉sciencedirect.com/science/articl…

🌍Great to see new publications coming from LMICs. 🍄Considerations after the 2nd International Collaborative Mycology Conference. 🧠The recommendations set a valuable example for other (LMI)countries! 📚🦠 pubmed.ncbi.nlm.nih.gov/39247871/

😷 Host is key once more in our fight against fungal infections! 🦠 Excessive influenza-induced IFN-γ impaired the Th17 immune response against aspergillosis in IAPA murine model. 💊 Is targeting this pathway the future? Laura Seldeslachts Greetje Vande Velde thelancet.com/journals/ebiom…

😷We need new antifungal strategies. 🧪But, recruitment in the (pragmatic) #HOVON502 study looking at #antifungal combination was difficult. 🍄Adding also low IA related mortality superiority trials seem unrealistic… Bart Rijnders Sammy Huygens @johanM94028778 academic.oup.com/cid/article/do…

A fantastic collaboration with Laura Seldeslachts, Greetje Vande Velde and Joost Wauters uncovering the immunological mechanisms underlying IAPA

#MucoralesPCR diagnosing mucormycosis and detecting mould coinfections much earlier than conventional methods, AND impacting the outcome with increased survival since introduction of the MucorPCR in France in 2015. No reason (not even financial) to not make the test available!

Important increase of #azoleresistance in Belgium the last years! With 9.7% especially in combination with a high incidence of mould coinfections (12%) reason to be careful with the clinical approach towards our frail patients. #aspergillosis Katrien Lagrou @johanM94028778

Posaconazole for Prevention of COVID‐19‐Associated Pulmonary Aspergillosis in Mechanically Ventilated Patients: A European Multicentre Case–Control Study Jürgen Prattes D.R. Giacobbe JP Gangneux Matteo Bassetti florian reizine philipp eller Robert Krause onlinelibrary.wiley.com/doi/full/10.11…

🚨🌟 EFISG Webinar Alert! 🌟🚨 🗓️February 18th, 15:00 CET 🩺 Invasive mould infections in conflict zones 🌍 1⃣ IFI in conflict zones 2⃣ Managing IFI in limited-resource settings 3⃣ Preventing IFI: Lessons from field hospitals 💻 Register now for FREE! us06web.zoom.us/webinar/regist…

ESCMID is celebrating the International Day for Women and Girls in Science with two leaders in our Society. Giulia De Angelis and Angela Huttner have spoken with us about the importance of this day and you can read here: ow.ly/LGMH50UXoCa #WomenInScience #WomenInSTEM

#EFISG fungal recommendations for #EFISGbroadcaster #ESCMID2025 #ESCMIDGlobal2025 ESCMID Fungal Infection Study Group (EFISG)

Azole resistance rates of Aspergillus fumigatus in Belgium have doubled over a 10-year period, from 4.6% in 2011 to 9.7% in 2022–2023. eurosurveillance.org/content/10.280…

🔥 Hot off the press from ESCMID Fungal Infection Study Group (EFISG)! #Candida endocarditis — rare, deadly (⚰️ up to 49% mortality), and still full of challenges: 🫀 Imaging 💊 Antifungals 😷 Surgery Read the latest review 👇 clinicalmicrobiologyandinfection.com/article/S1198-… #IDTwitter #FungalInfections