Check out our latest work identifying an excellent target for T cell-based vaccines against the liver stage of #malaria Cell Host & Microbe Doherty Institute UniMelb MDHS cell.com/cell-host-micr…

Want to know how CAR-T cells expressing Flt3L can induce DC expansion and promote endogenous CD8 responses? Check out this awesome study from Junyun Lai @mardianasherlz Prof Paul Beavis and others in Nature Immunology 👇

For those who'd like to read our @ImmunologyKing spotlight article on a exciting study from the Masopust Vezys Lab lab focussing on Trm plasticity, here's the free access link: authors.elsevier.com/c/1b8Uc5Eb0Rjf… Raissa Fonseca lalit beura Clare Quarnstrom Beura_lab@Brown

We are looking for a Research Assistant to join our group. Are you interested in T cell immunology or know some one who might be? This will be an excellent opportunity to learn and grow. Please apply-brown.wd5.myworkdayjobs.com/staff-careers-… Please RT.

Wondered what happens to #lungTRM when numbers contract? Check out our new exciting publication in Journal of Experimental Medicine. Great work by J. Michael Stolley, lalit beura @pcrosato1 Sathi Wijeyesinghe Ryan Langlois and colleagues!

Interrogating immune cells and cancer with CRISPR-Cas9 dlvr.it/RwmY8g #immunology

nature.com/articles/s4146…

.@K_Hochheiser et al identify Ptpn2 & KLRG1 as new regulators of CD103+ CD8+ TRM cells in skin. KLRG1 inhibits TRM formation, but genetic Ptpn2 deficiency increases the protective function of TRM cells in infection but aggravates TRM-dependent autoimmunity bit.ly/3sYxKzb

CD8 + and CD4 + T Cells Infiltrate into the Brain during Plasmodium berghei ANKA Infection and Form Long-Term Resid… pubmed.ncbi.nlm.nih.gov/34400523/ Proud of the nice imaging in our paper. Made the front cover too, for the first time in my career!

So excited to see this labour of love 🤍Susan Christo in press this morning! Read how tissue imprinting shapes Trm cell behaviour here!!👇Mackay Lab Maximilien Evrard Simone Park Raissa Fonseca Tom Burn Doherty Institute University of Melbourne UniMelb MDHS

Congratulations to our four DECRA recipients from the School of Biomedical Sciences! 🥳 Dr Carolien van de Sandt Dr Hui-Fern Koay Dr Justin Hardee Dr Raissa Fonseca 👏👏👏 biomedicalsciences.unimelb.edu.au/news-and-event…   Carolien van de Sandt Fern Koay 郭 Justin Hardee Raissa Fonseca

Meet Raissa Fonseca. A recent recipient of an ARC Discovery Early Career Research Award, she is looking into development of memory T cell responses. doherty.edu.au/news-events/ne… UniMelb MDHS Mackay Lab

Our first pre-print is out! Majority of this work was done in the Masopust Vezys Lab lab CFI-UMN with Noah Veis Gavil, MD, PhD in collaboration with Clark Chen and Jianfang Ning. Thank you to them and all coauthors! Eyob Weyu Sathi Wijeyesinghe Shawn Musial Sanjay Dhawan 1/8 biorxiv.org/content/10.110…

Happy to share new work from our lab WEHI (Walter and Eliza Hall Institute). Frustrated by the inability to activate heavily methylated genes Chan Wing Fuk fashioned a dCas9-TET1 based activation module he named TETact. Check it out 👇👇biorxiv.org/content/10.110…

I am pleased to have this out. #singlecell #multiomics to discover progenitor of #exhaustion in human viral specific CD8+ T cells (See below). Huge thank you to Raymond Louie @thiruni1 Dr Simone Rizzetto Kedzierska Lab Rowena Bull Preston L and others biorxiv.org/content/early/…

Congratulations to our researchers awarded $17.4 million in grants from NHMRC. Sharon Lewin Director impressed by the wide range of research spanning indigenous health, influenza, vaccine development and efficacy, and basic immunology. Read more: bit.ly/3zayS67

.Maximilien Evrard Mackay Lab and colleagues Doherty Institute find that S1PR5 expression impairs TRM cell differentiation by preventing T cell entry and promoting T cell egress from peripheral tissues bit.ly/3nluiOh

Have you ever wondered what controls tissue residency in CD8 vs CD4 T cells? Find out today! Nature Immunology go.nature.com/3zCkJlI 🧵👇 Amazing teamwork Raissa Fonseca Tom Burn Doherty Institute 🧑‍🔬

🌟Excited to share our latest work on how functionally distinct skin TRM utilise different pathways to establish residency, published today in Science Magazine! A true labour of love by BFF Simone Park and Susan Christo! 👩‍🔬 Doherty Institute University of Melbourne UniMelb MDHS science.org/doi/10.1126/sc…

Epithelial organoid supports resident memory CD8 T cell differentiation biorxiv.org/cgi/content/sh… #biorxiv_immuno