Day 2. Interesting talk by Lindsay Ulmer of the Bush Lab lab at UW given her take on increasing crosslinked PSMs using targeted DDA without inclusion lists increases the PSM count 8 fold #cascadiaproteomics

Great lightening talk by PhD candidate Alice Martynova Bush Lab on Unraveling Polarity-Specific ESI Mechanisms for Native Mass Spectrometry and the contribution of salt to neg ion ESI of proteins

Next up in #cascadiaproteomics is Deanna Plubell from the @MacCossLab telling us about the performance of the Thermo Fisher Stellar MS coupled with ReSyn Biosciences MagNet for highly multiplex targeted proteomics assays in biofluids

Up next is a lightening talk by Sophie Moggridge from the Judit Villen lab at UW on the phosphoproteome of stress granules, very under studied!

Another great Lightning Talk Keiann Simon at the Isoherranen lab at UW on the identification of Cannabinoid Metabolites and effect on human proteins by MS

Final by by no means least lightening talk before lunch is by Meghan McGrath by the Kelly Lee lab at UW on utilizing Mass Spectrometry to characterize the effect of Glycans on HIV Envelope Structure and Dynamics

Opening talk to the last session by Dr. Michal Maes from the Isoherranen lab at UW on the identification of novel protein adducts in ALDH1A enzymes using novel software tools Magnum/Limelight

Dr. Kristian Swearigen from the Rob Moritz lab ISB characterizing novel post-translational protein processing events as essential for virulence of the malaria parasite P. falciparum. Raises questions about the current Malaria vaccine and its efficacy

Very nice talk by Matthew Berg from the Judit Villen lab on a multidimensional proteomic approach to understand the impact of mistranslating tRNA variants. Using tools like automated phospho proteomics to delineate tRNA forced mistranslation

Penultimate talk by Alexis Chang from the Judit Villen lab with her latest and exciting nov pY superbinder phosphoproteomics data in multicellular interactions describing new obstacles and solutions to these challenges of semitryptic peptide generation

Final talk by powerhouse lab of Nick Riley at UW Chemistry describing their new tool for extracting informative glycan-specific ions from glycopeptide MS/MS spectra with oxonium ions called GlyCounter

BREAKING NEWS The Human genome and proteome is larger than we thought. Human Proteome ISB

BREAKING NEWS The Human genome and proteome is larger than we thought. Human Proteome ISB

Take a look at this paper in our latest issue by Verónica Rocío Vásquez-Garzón & co using proteomics to discover candidate biomarkers from plasma-derived extracellular vesicles of patients with cirrhosis & hepatocellular carcinoma 📍Facultad de Medicina pubs.rsc.org/en/content/art…

Don't miss this paper in our latest issue by Jianyu Chen, Xueqin Ma et al from Ningxia Medical University describing how serum metabolomics reveals the metabolic profile and potential biomarkers of ankylosing spondylitis Check it out in full below👇 pubs.rsc.org/en/content/art…

ISB & Rob Moritz congratulate University of Washington's David Baker & Google DeepMind's John Jumper & Demis Hassabis for the longterm development of in silico protein structural design. Fantastic achievement allowing mankind to visualize our bodies' machine parts in 3D. nobelprize.org/prizes/chemist…

A true trans-continental team effort of Philipp E. Geyer, Daniel Hornburg Maria Pernemalm, Stefanie Hauck, Krishnan Palaniappan, Vincent Albrecht Dr Laura Dagley Rob Moritz Xiaobo Yu Fredrik Edfors Yves Vandenbrouck Johannes B Müller-Reif, Zhi Sun, Virginie Brun, Sara Ahadi, Gil Omenn and Eric Deutsch

Don't miss this research in our latest issue by Philip J. Shaw, Yiqing Zhou & co Chinese Academy of Sciences elucidating the antimalarial mechanism of action of the natural product 9-methoxystrobilurin G by sequencing and chemoproteomics Check it out in full here🔽 pubs.rsc.org/en/content/art…

📢Our latest issue is now online! Check out the research behind the front cover by Anindita Seal & co Calcutta University Univ of Hyderabad investigating the bacterial endosymbionts of a nitrogen-fixing yeast Rhodotorula mucilaginosa JGTA-S1 pubs.rsc.org/en/content/art…

Take a look in our latest issue at a paper by Eric Leclerc, Amar Abderrahmani et al. on motif activity of transcription regulators in pancreatic β-like cell subpopulations differentiated from human induced pluripotent stem cells 📍Université de Lille UTokyo | 東京大学 pubs.rsc.org/en/content/art…