Janet Kumita, coming from Cambridge, is next. She will tell us about "The impact of N-terminally acetylated α-synuclein on designing therapeutic strategies to combat Parkinson’s Disease" #proteintermini24

Next, all the way from Seoul, we will hear from Min Ju Lee, presenting "Degradation of melanosome/melanin and chemical modulation of melanophagy by the N-degron pathway via p62/SQSTM1-dependent macroautophagy". #proteintermini24

Today's last (flash) talk, Samuel Madden, will tell us about "Plant Cysteine Oxidase (PCO) Oxygen -Sensing Function Is Conserved in Unicellular Algae" #proteintermini24

After a fruitful day of science! Conference dinner at Wadham College. #proteintermini24

Starting off the last day with some talks from FEBS representatives Matera Mancek Keber and Duncan Wright. #proteintermini24

First scientific talk of the day, Beatrice Giuntoli sharing some new insights on substrate discovery for plant Cys N-degron pathway. #proteintermini24

Elevator pitch time! First of the day is Rebecca Latter on ‘Modulation of Arabidopsis thaliana Plant Cysteine Oxidase 4 (AtPCO4) activity’. #proteintermini24

Next up, Ron Huang talking about new inhibitors for human N-terminal Methyltransferases. #proteintermini24

Last talk before the break, Mikie Kukwikila from Oxford Nanopore on new advances in protein sequencing. #proteintermini24

The terminal session of the protein termini meeting kicks off with Emmanuelle Graciet, diving into ‘The N-degron pathway’s role in the crosstalk between hypoxia signaling and plant immunity’. #proteintermini24

Next up: Jihoon Lee discusses ‘Targeted degradation of α-synuclein aggregates in Parkinson’s disease via the AUTOTAC chemical platform’. #proteintermini24

After some excellent work from Yong Tae Kwon, it is now time to hand over the baton to Carmela Giglione Giglione Carmela as new leader of the ISPT! Carmela will also be the host of the next ISPT conference in the sunny Palermo (June 2026)! Stay tuned 🎉 #proteintermini24

Next up, elevator pitch by Hye Yeon Kim on ‘A novel small-molecule AUTOTAC that selectively degrades pathological tau aggregates and improves outcomes in Alzheimer’s disease’. #proteintermini24

Thierry Meinnel (Université Paris-Saclay) presents his work on ‘Novel, tightly structurally related N-myristoyltransferase inhibitors with potent yet distinct inhibitory mechanisms’. #proteintermini24

Final talk of the session and the meeting, Daniel Youngjae Park (Seoul National University) presents ‘Targeted Protein Degradation as a Novel Therapeutic Approach Against Amyotrophic Lateral Sclerosis (ALS)’. #proteintermini24

Congratulations to the winners of the best Poster prize - Samuel Zolg, Dani Amat and Anna Dirr. Best talk - Mahima Bhat. #proteintermini24

Just back from an excellent ISPT_ProteinTermini meeting in Oxford. Lovely to catch up with #proteostasis friends and hear about the latest results. Big thanks to Emily Flashman, . and the team for organising 👏

Our recent publication led by Ying Meng Purdue Borch MCMP explores how NTMT1-mediated Na-methylation affects the stability and interaction of PAD1, offering insights into protein N-terminal methylation. Great contributions on proteomics by Wang lab at UCR. pubs.acs.org/doi/full/10.10…