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The recent Conference on Retroviruses and Opportunistic Infections 2025 was a moving tribute to the importance of HIV research and efforts to eradicate HIV globally. Presentations are now up online. It was a great honor to deliver the Fields Lecture! croiwebcasts.org/console/player…

Prokaryotic Seminar 🦠 Monday 4/21/25 4-5PM 209 Johnson Pavilion Subham Mridha, PhD, Abt Lab “Dissecting immune driven adaptive evolution of Clostridioides difficile within the intestinal lumen”

Virology Seminar 💉 Tuesday 4/22/2025 12-1 PM 209 Johnson Pavilion Join Nicole Bracci, Ph.D., Weiss Lab “The Cooperative Impact of Coronavirus Innate Immune Antagonists”

📢There will be *NO* Microbiology Seminar on Wednesday April 23rd.

Congrats to Marie Seleme, Aradhana Kasimsetty and the team on their report of effective methods for increasing expression from AAV vectors by blocking SUMOylation. Effective boosting by treatment with an inhibitor presently under investigation in humans! (PMID: 40263936)

Microbiology Seminar 🔬 Mark your calendars! Please join us for the annual -Neal Nathanson Lecture- Wednesday 4/30/25 12-1PM CRB Austrian Auditorium Bruce Walker, MD "HIV as a model for immune control and immune failure: Insights from Africa" ragoninstitute.org/bruce-d-walker/

Microbiology Seminar 🔬 Please join us for the annual -Neal Nathanson Lecture- This Wednesday! Wednesday 4/30/25 12-1PM CRB Austrian Auditorium Bruce Walker, MD "HIV as a model for immune control and immune failure: Insights from Africa" ragoninstitute.org/bruce-d-walker/

Microbiology Seminar 🔬 Please join us for the annual -Neal Nathanson Lecture- TODAY! Wednesday 4/30/25 12-1PM CRB Austrian Auditorium Bruce Walker, MD "HIV as a model for immune control and immune failure: Insights from Africa" ragoninstitute.org/bruce-d-walker/

Thanks so much to Bruce Walker for the moving talk on HIV immunology and mitigating AIDS in Africa. It is heartbreaking that federal cuts to PEPFAR over the next four years are projected to result in 4 million additional deaths and 6 million additional infections (UNAIDS).

Prokaryotic Seminar 🦠 Monday 5/5/25 4-5PM 209 Johnson Pavilion Jacob Cote, Pohlschroder Lab “Mutants in Motion: Identification and Characterization of Novel Motility Regulation Genes in the Model Archaeon Haloferax volcanii”

Virology Seminar 💉 Tuesday 5/6/2025 12-1 PM 209 Johnson Pavilion Nikki Tanneti, PhD, Weiss Lab "Risk factors for MERS-CoV infection" Gabby Scher, PhD, Hensley Lab “Effects of prior immunization with a 20HA mRNA-LNP vaccine on subsequent heterologous HA mRNA-LNP vaccinations”

Please join for a Special Seminar 5/12/25 12pm 209 Johnson Pav Melissa Smith PhD, Department of Biochemistry & Molecular Genetics, University of Louisville. “Decoding diversity: genomic technologies for characterizing the host-pathogen relationship” louisville.edu/medicine/cance…

Virology Seminar 💉 5/13/25 12-1 PM 209 Johnson Pavilion Helena Winstone, PhD, Weiss Lab “Mapping Spike determinants of MERS-CoV spillover” Amber Abbott, Weitzman Lab “High-throughput identification of RNA-binding protein localization patterns altered during adenovirus infection”

Microbiology Seminar 🔬 *Last Spring Seminar* Wednesday 5/14/25 12-1PM CRB Austrian Auditorium Tim Sheahan, PhD "Preparing for Tomorrow’s Pandemics Today: Broad spectrum antivirals for emerging coronavirus infections" sph.unc.edu/adv_profile/ti…

Contrats to Saira, Kushol and the team on an important publication on HIV integrase structure and inhbitor resistance. Escape from allosteric inhibitors is associated with notable conformational changes. PMID: 40409709

In case you were wondering why research is important: check out the song from Mags McCarthy and Bruce Levine on saving lives with novel cancer therapy: youtube.com/watch?v=dkOrbj…

Congrats Stephen Bagley DrORourke and colleagues Penn Medicine - Abramson Cancer Center on their manuscript in Nature Medicine showing safety and early efficacy of bivalent CAR T cells in 18 patients with recurrent #glioblastoma! nature.com/articles/s4159…

🚨NEW REVIEW- The Next Innovations in Chimeric Antigen Receptor T Cell Immunotherapies for Cancer -Armored CAR T cells -Genetic Enhancement of CAR T cells -In Vivo CAR T Cell Therapy @isctglobal @Cytotherapy #immunotherapy sciencedirect.com/science/articl…

BREAKING: A federal judge on Monday dismissed a December 2023 lawsuit against Penn that alleged the University had not sufficiently responded to campus antisemitism. l8r.it/Ks30

Congrats to Lydia Mendoza and the team on their latest publication: detailed characterization of immune responses against recent influenza strains at the Hospital at the University of Pennsylvania. PMID: 40452165.