About a month after Donald Trump took office as the 47th US president, almost all grant-review meetings remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion

Without NIH funds to run research labs at academic institutions, as a country we cannot train PhD students. No physician scientists. No undergraduates get experience in labs. Nothing. Industry does none of these things. Other countries will have to take the lead.

The Trump administration's efforts to slash research funding have US graduate students, postdocs and other early-career scientists fearing for their careers. Some are considering changing jobs or leaving the country. Others say them might abandon research altogether.

SERENA-6: ctDNA guided approach to switching from AI to camizestrant upon development of ESR1m in combo with cdk4/6i demonstrates improvement in PFS! PFS2 + OS immature Could be a paradigm shift + could introduce ctDNA monitoring into practice astrazeneca.com/media-centre/p…

Incredibly proud of Evangelia (Elina) Vlachou, MD for matching at The Osler Medical Residency! She’s got a bright future ahead in oncology—can’t wait to see all she’ll accomplish! Jean Hoffman-Censits Johns Hopkins Kimmel Cancer Center

Excited to share our multicenter retrospective cohort study of ADC sequencing is now published in NPJ Breast! rdcu.be/ehTr6 Thanks to our co-authors for this great team effort! Hope Rugo Reshma Mahtani Ruta Rao

A lot is happening in breast cancer! ASCENT-04 reports improvement in PFS for sacituzumab + pembro vs TPC+pembro in 1L mTNBC, & DESTINY-Breast09 reports improved PFS for TDXd+P vs THP in 1L metastatic HER2+ breast cancer! Nice to see new options for our pts!

🚨Thrilled to share our latest work: “Tumor-Infiltrating Clonal Hematopoiesis” NEJM - we investigated how age-related blood mutations impact cancer when they infiltrate tumors, with Elsa Bernard Maria Zagorulya, Elli Papaemmanuil, PhD Charles Swanton + more nejm.org/doi/full/10.10…

If you are at AACR and interested in breast cancer and #immunotherapy swing by poster section 28 #3225 from 2-5pm today to learn about our metaanalysis on dual PD-(L)1i+CTLA4i and single PD-(L)1i IO in pretreated pts with #mTNBC! #bcsm Johns Hopkins Kimmel Cancer Center USC Norris Comprehensive Cancer Center MD Anderson Cancer Center

Join me and my colleagues for a Medical Crossfire satellite symposium focused on Integrating Next-Generation Endocrine-Targeted Therapies for HR+/HER2- BC at #ASCO25. Register here: tinyurl.com/tmbkzkec Looking forward to a great discussion in Chicago!

I am thrilled to receive the 2025 ASCO / Conquer Cancer, the ASCO Foundation Young Investigator Award! I am deeply grateful to my mentors at Johns Hopkins Kimmel Cancer Center Johns Hopkins Hematology and Oncology Fellowship for their unwavering support and guidance throughout three transformative years of fellowship.

In 2022, Janice Cowden , Dear Dr. Researcher, PhD, & I sat together to hear the much anticipated DESTINY-Breast 04 trial results. As cancer survivors, when we see data, we see the patients behind the data, we ARE the patients behind the data, & we’re grateful to still be here! #ASCO25

Congratulations to our 🌟 Johns Hopkins Hematology and Oncology Fellowship fellows Drs. Ferreira, Liang, Mo, Walsh and Zavras on their ASCO Conquer Cancer, the ASCO Foundation Young Investigator Awards. And to our alumna/phenomenal faculty member Marina Baretti on her CDA! So incredibly proud of their hard work & dedication 🤩🙌🏼

Congratulations to our 2025 ASCO Oncology Young Investigator Award recipients! 🎉 Phaedon D. Zavras Phaedon Zavras 🎉 Laura Walsh 🎉 Shirley Mo 🎉 Kai-li Liang Kai-li Liang 🎉 Michelle Ferreira And recent fellowship graduate and CDA recipient Marina Baretti Marina Baretti

Honored/humbled to be inducted as Fellow of ASCO (FASCO) along with many stellar colleagues/friends! United in the mission vs cancer Vamsi Velcheti, MD MBA FASCO Jason Westin, MD FACP FASCO Sandip Patel MD FASCO H. Jack West, MD, FASCO Lucky Lara Lynn Schuchter Julie Gralow Clifford Hudis Eric J. Small, MD, FASCO Fred Hutch Cancer Center Dr. Tom Lynch

Always a joy to reunite with this phenomenal group of breast oncologists! Huge congratulations to all on the well-deserved YIAs—and a big thank you to Conquer Cancer, the ASCO Foundation and ASCO for their continued support of early-career investigators. #ASCO25

#ASCO25 #OncTwitter #crcsm NEW: Randomized trial of exercise vs health ed in people w/ colon cancer post adjuvant chemo: disease-free (HR 0.72; 6.4% abs diff at 5y) & overall (HR 0.63; 7.1% abs diff at 8y) survival improved w/ exercise! NNT ~14. ACTUALLY tolerable. 🏆 #OncoAlert

This is a major story from #ASCO25. Randomized phase 3 trial of time of day of immunotherapy infusion. Randomized to infusion before or after 3pm. Early infusion far superior: PFS 11.3 vs 5.7 HR 0.42, OS HR 0.45! Impactful, pragmatic, not costly. This should be a bigger story.

Celebrating our brilliant grant & award recipients at #ASCO25! 🤝 It was inspiring to see them network & connect. View & download photos from the full gallery: brnw.ch/21wTCQc #ConquerCancer #CancerResearch

🎓Congratulations to our outstanding Johns Hopkins Kimmel Cancer Center oncology fellows on their graduation! We're so proud of all you've accomplished and excited to see the impact you’ll make in the field. Here's to the next chapter!