
Elli Papaemmanuil, PhD
@papaemmanuillab
Computational Oncology. Explores 🧬 tech, algorithms & data to improve diagnosis & treatment decisions in oncology. Opinions my own. Disclosures: bit.ly/3wpiP60
ID: 3154223927
http://www.isabl.io 10-04-2015 18:30:28
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Hanging out with some of the very best SocforHemepath #USCAP2025 Plus today I found out that dreams do come true... looking forward to a trully unifed classification for heme malignancies in the next WHO 📘 Let's get this done right this time!

👇me and Elli Papaemmanuil, PhD with front row seats at packed Edwin Cuppen / Hartwig Medical-organized clinical cancer genome conference, rapt as Charles Swanton keynote unpacks ~5-10 years worth of unpublished data from his lab to basically solve never-smoker lung cancer 😮😲🙀🤯




Excited to share our paper out today in Cell Press discovering RNA mis-splicing derived neoantigens & their cognate T cell receptors (TCRs) as well as characterization of endogenous neoantigen T cells in leukemia patients. authors.elsevier.com/sd/article/S00…


Some trully trainee led science! Elsa Bernard Oriol Pich Maria Zagorulya - our work is done here! Read how CH can influence solid tumor progression & treatment response ⬇️ NEJM with the one & only Charles Swanton Memorial Sloan Kettering Cancer Center The Crick

It has been unclear why cancer patients with CH have worse outcomes. Our work published NEJM uncovers that Tumor infiltrating CH (TI-CH) has a direct role in immune remodelling of the TME with implications for tumor progression & treatment response. Memorial Sloan Kettering Cancer Center The Crick



Phenotyping recurrent genomic architectures. Led by Maria Sirenko Soobeom Lee & Z. Sun, our study Cell Stem Cell shows how patterns of co-mutations shape lineage composition + drive diverse cellular programs in AML. Awesome collaboration with Dan Landau Iannis Aifantis++🧵⬇️

On the eve of #ASCO25, it's #AcuteMyeloidLeukemia Thursday. Here are Top Posts of the Week! 🎉🎉🎉 1/ Elli Papaemmanuil, PhD on how patterns of co-mutations shape lineage composition + drive diverse cellular programs in AML: x.com/PapaemmanuilLa…

🚨🚨Paper out! 🚨🚨 Delighted to share our work, now published in Nature Genetics 🧬! shorturl.at/94s5S We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n 🧵👇


Excited to share our latest study, led by Curtis Lachowiez & Sanam Loghavi, MD صنم لغوی 🔬🧬 on the relevance of data informed metrics in setting guidelines for disease classification in myeloid neoplasms.