Ozlem Dmr (@ozlem__dmr) 's Twitter Profile
Ozlem Dmr

@ozlem__dmr

#CompChem #DrugDiscovery Opinions & views are solely my own.

ID: 1236506905981251586

calendar_today08-03-2020 04:21:25

1,1K Tweet

256 Followers

1,1K Following

Science Magazine (@sciencemagazine) 's Twitter Profile Photo

Analysis of blood samples from patients with #LongCovid has revealed serum protein changes as the likely culprit. The results show potential biomarkers for diagnosis and could yield insights into treatment. scim.ag/5FX #SciencePerspective: scim.ag/5FW

Analysis of blood samples from patients with #LongCovid has revealed serum protein changes as the likely culprit. The results show potential biomarkers for diagnosis and could yield insights into treatment.

scim.ag/5FX
#SciencePerspective: scim.ag/5FW
Science Magazine (@sciencemagazine) 's Twitter Profile Photo

A large-scale, whole-genome analysis in Science of over 12,000 cancers reveals previously unreported mutational signatures, including tumor-specific rare signatures. The findings may enhance personalized cancer treatments and diagnoses. #WorldCancerDay scim.ag/5KY

A large-scale, whole-genome analysis in Science of over 12,000 cancers reveals previously unreported mutational signatures, including tumor-specific rare signatures.

The findings may enhance personalized cancer treatments and diagnoses. #WorldCancerDay scim.ag/5KY
JCIM & JCTC Journals (@jcim_jctc) 's Twitter Profile Photo

Development of a Fluctuating Charge Model for Zinc-Containing Metalloproteins #Metalloproteins #MolecularDynamics pubs.acs.org/doi/10.1021/ac… #JCIM Vol64 Issue3 #compchem

Adrian Roitberg 🏳️‍⚧️ (@adrian_roitberg) 's Twitter Profile Photo

It is my pleasure to announce the fruits of a great collaboration with people at SandboxAQ A diffusion model, end to end differentiable, optimizing many functions at once. In this example, we optimized binding affinity and synthetic accessibility. arxiv.org/abs/2405.11785.

David R. Liu (@davidrliu) 's Twitter Profile Photo

Today we report in Nature Biomedical Engineering the systematic application of six recent prime editing developments to enable efficient and functional correction of CFTR F508del, the predominant mutation that causes cystic fibrosis (CF), in primary airway cells from CF patients.

Today we report in <a href="/natBME/">Nature Biomedical Engineering</a> the systematic application of six recent prime editing developments to enable efficient and functional correction of CFTR F508del, the predominant mutation that causes cystic fibrosis (CF), in primary airway cells from CF patients.
Lorenzo Casalino (@lcasalino88) 's Twitter Profile Photo

In our new study out in Nature Communications, co-led by Xandra Nuqui and myself, in collab. w/ Jason McLellan & Kartik Chandran, we designed a 2W-stabilized SARS-CoV-2 S2 antigen exhibiting enhanced expression and preserved immunogenicity against sarbecoviruses. 👉 nature.com/articles/s4146…

In our new study out in <a href="/NatureComms/">Nature Communications</a>, co-led by <a href="/xandra_nuqui/">Xandra Nuqui</a> and myself, in collab. w/ <a href="/McLellan_Lab/">Jason McLellan</a> &amp; <a href="/ChandranLab/">Kartik Chandran</a>, we designed a 2W-stabilized SARS-CoV-2 S2 antigen exhibiting enhanced expression and preserved immunogenicity against sarbecoviruses.

👉 nature.com/articles/s4146…
Jen Heemstra (@jenheemstra) 's Twitter Profile Photo

No proposal or manuscript is ever perfect, but to be effective, it does eventually need to be finished. Nothing we submit will ever be as good as it *could* be and just recognizing that can be an important step forward. Perfection is not the goal. Finished is the goal.

Rommie Amaro (@rommieamaro) 's Twitter Profile Photo

New work on protein design... 🚨S2 immunogen design using advanced simulation WESTPA Software WE MD--> opening mechanism--> design--> stabilized protein--> cryoEM structure + immunology Xandra Nuqui Lorenzo Casalino Jason McLellan Kartik Chandran nature.com/articles/s4146…

Adam Broerman (@adam_broerman) 's Twitter Profile Photo

Excited to announce our new #proteindesign strategy for allosterically controlling the kinetics of protein-protein interactions! Read on for cool applications in cytokine signaling, biosensing, and protein circuits. biorxiv.org/content/10.110…

Institute for Protein Innovation (@ipiproteins) 's Twitter Profile Photo

The Baker Lab @UWProteinDesign recently hosted this powerful webinar on computational protein design. Take a journey through the history of this groundbreaking field, guided by some of the greats! youtube.com/live/BuJGTn7Oh…

Dr. Catharine Young (@catgyoung) 's Twitter Profile Photo

The next Einstein, Curie, or Salk might be sitting in a lab right now, wondering if they should quit. Don’t let them. Fund science like the future depends on it…because actually it does.