The calm after a 🔥 #Rimini night as day 2 of #EMBOCancerEvo is about to start - wonderful science, great atmosphere and frankly the best location ever EMBO Luca Magnani Leila Akkari Giovanni Ciriello Anna Obenauf

And my brilliant friend Renato Ostuni giving us an overview of the central role of IL1b TAMs in inflammation prior to and during pancreatic cancer, with very thought provoking perspectives 🤩🤩#TMFOCE #Rimini

Closing the lights of the #RockIsland after 3 amazing days of science and fun and food and spritz #EMBOcancerEvo #TMFOCE Hope you all enjoyed this second edition The Many Faces of Cancer Evolution, it was a blast! Thank you and see you all in 2 years 😉

📣📣📣Mark your calendars (Feb 2-5, 2025) for the next innate immune memory keystone symposium organized by Renato Ostuni Keke Fairfax, PhD and me, with a special PRESIDENTIAL Keynote by Belkaid Lab. #KSinnateimmune25 Keystone Symposia. Deets👇🏼👇🏼👇🏼 keystonesymposia.org/conferences/co…

📍See u in Vancouver (Feb2-5) for THE Keystone Symposia on innate immune memory! We got scientists across fields to share unique ideas on what cellular memories are and how they transmitted to shape human biology - in immunity and beyond 🤯 #KSinnateimmune25 Dr. Shruti Naik Keke Fairfax, PhD

Join us in Vancouver Dr. Shruti Naik Renato Ostuni and myself have organized a fantastic meeting featuring all aspects of Innate immune memory. ECR Submit abstracts early for a chance at a short talk!

Great fun visiting CNIO Stop Cancer and hear some of the great science cooking there! Thanks for having me Nabil Djouder Casanova Acebes Lab Paco Real, Alejo Efeyan &more

Check out the latest from Iannacone Lab in Cell 🔥 Matteo and team keep on revealing new biology of liver T cells in HBV with massive therapeutic implications

I had a great visit to San Raffaele in Milan last week, which is stacked with great science and translational medicine. Thanks Roza Barouni for organising! Renato Ostuni Iannacone Lab Ospedale San Raffaele (and good luck Renato with your extreme marathon)

How to predict a futile upfront resection for resectable #PDAC (death/recurrence within 6mo)? 💥 JAMA Surgery paper with MetroPancreas model based on Ca 19-9, ASA and tumor size 👉Online calculator aicep.website/metropancreas/ ➡️ jamanetwork.com/journals/jamas…

Back from a CRAZY race Eiger Ultra Trail in the Swiss Alps. 250km, 15000m climbing, 84 hrs total, 3h sleep. As a scientist & ultrarunner, I wonder what new biology we'd find studying our body adaptation (good/bad) to extreme exercise. Anyone up for a crazy grant application? 😎

Stem cells "steal" CXCR4 from bone marrow macrophages to persist longer in their niche - Cool stuff in Science Magazine science.org/doi/10.1126/sc…

Paper 🚨! Ecstatic, proud, grateful …Years of dedication from the whole lab, with the exceptional Daan J. Kloosterman and the one of a kind #JohannaErbani at its helm. What a journey all the way to Cell! How did it start (& end)? A 🧵1/n cell.com/cell/fulltext/…

Immunosuppressive Lipid-laden macrophages (LLM) eat myelin debris in brain tumors and transfer digested lipids to cancer cells, fueling malignancy - Massive paper out by Leila Akkari lab in Cell cell.com/cell/fulltext/…

👇👇👇 informative tweetorial by Leila Akkari - btw, this is what by brain pictured when thinking how macrophages feed cancer cells in GBM

Not one, not two, ALL 3 variants of SWI/SNF nucleosome remodelers are needed to generate latent/de novo enhancers in activated macrophages - kudos to HargreavesLab Immunity for solving a key issue since the discovery of these elements cell.com/immunity/fullt…

If you were a postdoc now, what would you study? My #1 choice: PROTEIN ENGINEERING Beautifully exemplified by this Nature Communications by David Baker Institute for Protein Design - De novo design of mini-proteins that potently inhibit IL-1 and IL-6 signaling nature.com/articles/s4146…

"Salty" 🧂🧂🧂papers out Nature Immunology! NaCl boosts CD8 T cell fitness and cytotoxicity for cancer immunotherapy Massive congrats Lugli Lab and Zielinski lab for this important discoveries nature.com/articles/s4159… nature.com/articles/s4159…

Science is back strong Ospedale San Raffaele Università Vita-Salute San Raffaele as Eileen Furlong EMBL walks us through the amazing biology of enhancers

#SITC24 Science Preview: Jennifer Guerriero, PhD @Brighamsurgery, Alberto Mantovani, MD, Instituto Clinico Humanitas, Lai Guan Ng, PhD, Shanghai Immune Therapy Institute, Miriam Merad, MD, PhD Icahn School of Medicine at Mount Sinai, Renato Ostuni Università Vita-Salute San Raffaele explore myeloid cells in cancer. Details: ow.ly/lj5M50TguxT