Modified-release (MR) vs immediate release (IR) opioids Patients who received MR (vs IR only) following surgery: • had 2.76-fold higher odds of experiencing an opioid-related adverse event during inpatient stay • had worse pain during the first 24 h postoperatively

Congrats Shania Liu

Modified-release opioid use (compared with immediate-release opioids) after surgery was associated with: • a higher incidence of opioid-related adverse events • worse pain • no superiority for analgesic consumption or physical function There is increasing evidence to

Risks and benefits of oral modified-release compared with oral immediate-release opioid use after surgery: a systematic review and meta-analysis Shania Liu Sid Patanwala Nicholas Levy Jennifer Stevens Dileep Lobo Jonathan Penm, PhD, FFIP FAdPha FPS FANZCAP FHEA buff.ly/4gInDZx

Honoured to see our work on safe #opioid prescribing after #surgery featured as one of 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 most impactful papers of 2023! APSIG_IASP IASP Australian Pain Soc University of Sydney Institute for Musculoskeletal Health Andrew McLachlan

Great to watch your impact on international clinical practice . Many congratulations

Nicholas Levy Jonathan Penm, PhD, FFIP FAdPha FPS FANZCAP FHEA and fellow #Ausdie Shania Liu are now committee members of APSIG_IASP. Rianne van Boekel and I are delighted to have them on board.

Really proud of this one. Such a great effort; a great idea concieved by Nicholas Chrimes and refined by the whole team. Hopefully, its findings will inform future guidelines and clinical teaching, and who knows… perhaps even help save a life or two.

SGLT2’s Ketosis is an issue….particularly when starved already! #11EMCCPMC #FOAMed #POCUS #FOAMcc #medtwitter @Cheapoflurane Caz Sampson Midlands Medical Conferences CIC (Not for Profit)

Final version of preoperative pain guidelines published today. …-publications.onlinelibrary.wiley.com/doi/10.1111/an… Nicholas Levy Kariem Helen Laycock Bill Fawcett Felicia Cox FRCN 💙 💛 Will Eardley Dr Zoey Malpus Anjna Patel Cathy Price 💙🇺🇦🏴󠁧󠁢󠁷󠁬󠁳󠁿 1 @nabualaw Association of Anaesthetists The British Pain Society

Final version published now Neurogastro & Motil ANMS ESNM.eu @UoN_GI_MRI onlinelibrary.wiley.com/doi/10.1111/nm…

⚠️ Discharge opioids The current quantities of opioids provided at discharge exceed patient needs & may contribute to increasing community opioid use and circulation. TASMAN Collaborative Lorane Gaborit Chris Varghese buff.ly/3Ohgz9f

Kariem Nicholas Levy Association of Anaesthetists Ketan Dhatariya …-publications.onlinelibrary.wiley.com/doi/10.1111/an…

…-publications.onlinelibrary.wiley.com/doi/10.1111/an… Kariem Ketan Dhatariya Nicholas Levy Association of Anaesthetists ERAS® Society

Professor Nicholas Levy delivering a wonderful Featherstone oration Association of Anaesthetists Winter Scientific Meeting. #WSM2025 “Challenging pseudoaxioms to improve perioperative care” Nicholas has introduced many changes for surgical patients with diabetes and safe opioid usage.

Recommendations for the peri-operative management of patients taking glucagon-like peptide-1 receptor agonists and glucose-dependent insulinotropic peptide Kariem Jugdeep Dhesi @nicholaslevy Dileep Lobo Omar Mustafa Philip Newland-Jones Dimitri Pournaras Ketan Dhatariya #anaesthesia

The development & implementation of a clinical decision support tool for acute pain management improved analgesic prescribing practice and promoted opioid stewardship at the point of prescribing. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2… Nicholas Levy British Journal of Anaesthesia ESRA | European Society of Regional Anaesthesia

Our case report on the safe use of HCL technology in emergency surgery in a person with type 1 diabetes. There are very few data on perioperative HCL use. …-publications.onlinelibrary.wiley.com/doi/10.1002/an… Nicholas Levy

publishing.rcseng.ac.uk/doi/epdf/10.13… Nicholas Levy Jonathan Houdmont

Is there scope for improvement in the knowledge base of resident doctors on fluid and electrolyte prescribing?