
Michelle Trenkmann
@mt_genetics
Love science. Senior Editor @Nature, previously @NatureComms. If it's not science, I'll probably be in the gym or the kitchen (also science). All views my own.
ID: 3299055988
26-05-2015 09:23:27
654 Tweet
1,1K Followers
232 Following



Today we publish 1st Human Pangenome Reference Consortium Reference Consortium primary research paper nature. Highlights: Near #T2T complete & error-free diploid human genome; phasing haplotypes in assembly graph is best; 50% of total genetic variation is in the centromeres nature.com/articles/s4158…


How do the #genome, #epigenome and #transcriptome co-evolve in colorectal #cancer? In the second of two papers in @nature, we find gene expr is not strongly heritable & evaluate "driverness" of muts directly in patient tumours nature.com/articles/s4158… Andrea Sottoriva #EPICC2 1/7


Out today in @nature : nature.com/articles/s4158… - some steps toward understanding cell-to-cell genomic variation in cancer. Joint work with Samuel Aparicio lab (now 15yr collab!). Work performed by Tyler Funnell Marc Williams Ciara O'Flanagan and teams from both labs.


So excited to share our work on the genetic architecture of rare coding variation, now published in nature nature.com/articles/s4158… This work was led by superstar co-first authors Dan Weiner, MD PhD and Ajay Nadig


