Welcome Christian Göritz on Jan 23rd. Excited to hear about your research on perivascular fibroblasts, scarring and regeneration of the central nervous system. The seminar is part of the Stem Cell Seminar series and open to all Life Sciences University of Helsinki Medicine and Health, University of Helsinki HiLIFE_Helsinki

New collaborative study of Hannes Lohi lab together with Henna Tyynismaa lab Julius Rönkkö from our CoE. Surprising findings in Lancashire Heeler dogs shed light on CMT disease mechanisms journals.plos.org/plosgenetics/a… Congratulations to all authors! University of Helsinki Suomen Akatemia | Research Council of Finland

Tomorrow, welcome!

Online Now! Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin dlvr.it/TJMj7h #stemcells

Proudly presenting Sharif’s paper on the role of Asporin in intestinal regeneration through TGF-B-dependent fetal-like reversion sciencedirect.com/science/articl… out now in Cell Stem Cell University of Helsinki Suomen Akatemia | Research Council of Finland Institute of Biotechnology (BI) @MIBS-Helsinki Pekka Katajisto Read our thread on Bluesky🦋

Welcome to the next Metabolism seminar, March 18th at 9-11 am in Meilahti. Excellent speaker lineup with and Kirsi Pietiläinen and Robin Cristofari groups presenting about #obesity #adiposetissue #diet #aging in humans and penguins STEMM Research Program Institute of Biotechnology (BI) Medicine and Health, University of Helsinki

The Katajisto Lab modeled #epithelial regeneration using small intestinal scaffolds and identified #asporin is a mediator of fetal-like reprogramming. Read the Cell Stem Cell article: bit.ly/41LJbhn Listen to the conversation: bit.ly/3FBkNHR

Next Stem Cell Seminar April 23rd, welcome! bsky.app/profile/metast… Medicine and Health, University of Helsinki HiLIFE_Helsinki STEMM Research Program Institute of Biotechnology (BI) FIMM HelsinkiUni

Happy to present Hien’s paper on age-selective apportioning of peroxisomes as a fate determinant in adult stem cells nature.com/articles/s4146… MetaStem University of Helsinki Karolinska Institutet Institute of Biotechnology (BI) @MIBS-Helsinki Suomen Akatemia | Research Council of Finland out now in Nature Communications Congrats Hien Bui et al!

A new study from our CoE finds that stem cells can control whether they self-renew or differentiate by localizing certain metabolic reactions differently helsinki.fi/en/faculty-bio… Suomen Akatemia | Research Council of Finland University of Helsinki Katajisto Lab Institute of Biotechnology (BI) @MIBS-Helsinki Hien Bui Pekka Katajisto

New from our CoE by Katajisto Lab show how tissue stem cells can metabolically regulate tissue renewal and differentiation by providing daughter cells with peroxisomes of different age and metabolic properties nature.com/articles/s4146… Suomen Akatemia | Research Council of Finland University of Helsinki HiLIFE_Helsinki

News from our CoE by Henna Tyynismaa group characterize the role of mitochondrial intermembrane space protein CHCHD10 in metabolism and spinal muscular atrophy Jokela type (SMAJ) actaneurocomms.biomedcentral.com/articles/10.11… Congratulations Sandra Harjuhaahto! Suomen Akatemia | Research Council of Finland University of Helsinki STEMM Research Program

Proudly presenting Simon’s paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism Nature Metabolism nature.com/articles/s4225… University of Helsinki HiLIFE_Helsinki Suomen Akatemia | Research Council of Finland MetaStem

News from our CoE by OtonkoskiLab Eliisa Vähäkangas et al show that upon engraftment into mice stem cell derived pancreatic islets become insensitive to pyruvate, correlating with down regulation of pyruvate/lactate transporter MCT1 link.springer.com/article/10.100… Suomen Akatemia | Research Council of Finland University of Helsinki

News from our CoE by Katajisto Lab Andersson et al found that intestinal stem cells with old mitochondria make Paneth cells faster due to higher aKG levels and aKG improves regeneration in old animals by Paneth cell renewal nature.com/articles/s4225… Suomen Akatemia | Research Council of Finland University of Helsinki